Targeted combined therapy in 2D and 3D cultured MCF-7 cells using metformin and erlotinib-loaded mesoporous silica magnetic nanoparticles

N Hashemzadeh, A Aghanejad… - Journal of …, 2021 - Taylor & Francis
Aim This research aims to develop potential therapeutic nanostructures (NSs) encapsulating
metformin (MET) and erlotinib (ER) for combinational therapy in breast cancer. Methods …

[HTML][HTML] Epithelial transfer of the tyrosine kinase inhibitors erlotinib, gefitinib, afatinib, crizotinib, sorafenib, sunitinib, and dasatinib: implications for clinical resistance

RJ Honeywell, I Kathmann, E Giovannetti, C Tibaldi… - Cancers, 2020 - mdpi.com
… We compared gut absorption of inhibitors of epidermal growth factor receptor (erlotinib,
gefitinib, and afatinib), ALK-cMET (crizotinib), PDGFR/BCR-Abl (dasatinib), and multikinase …

A comparative study evaluating the quality of life in patients receiving chemotherapy versus oral TKI in the third line and beyond setting for advanced non–small-cell …

NS Menon, V Noronha, VM Patil, AC Singh… - 2023 - ascopubs.org
… Patients were randomised to receive chemotherapy(Gemcitabine/docetaxel/paclitaxel/vinorelbine)
or TKI (erlotinib or gefitinib). Patients were evaluated at every visit for clinical benefit …

Elucidating the significance of amphiregulin and its implications for EGFR inhibition strategies in LKB1-mutant NSCLC

XK Solone, X Zhou, M Yu, JW Li, F Rimay, F Kaye… - Cancer Research, 2024 - AACR
comparative studystudy revealed that LKB1 loss increases AREG, triggering aberrant
EGFR signaling critical for lung cancer growth, and AREG expression might impact the Erlotinib

Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: a synergistically promising approach for cell proliferation prevention and ROS-Mediated …

L Asadollahi, A Mahoutforoush, SS Dorreyatim… - International Journal of …, 2022 - Elsevier
… To take a look at whether or not induction of cell cycle arrest contributed to the antiproliferative
efficiency of erlotinib and resveratrol in non-small lung cancer cells, we carried out cell …

[HTML][HTML] Randomized phase III study of docetaxel versus docetaxel plus intercalated erlotinib in patients with relapsed non-squamous non-small cell lung carcinoma

…, EF Smit, JGJV Aerts, NVALT Study Group - Lung Cancer, 2021 - Elsevier
… However opposed to our study, the maintenance therapy consisted only of erlotinib
monotherapy and not of a combination with docetaxel and patients were not selected on EGFR-WT …

Nevoid melanoma and eruptive nevi from erlotinib

JS Seidman, DZ Eichenfield… - Dermatology Online …, 2020 - escholarship.org
erlotinib has been associated with a variety of adverse … eruptive nevi while on erlotinib for
metastatic lung cancer. … one prior report of eruptive nevi related to erlotinib [7], which was part …

Chemosensitivity assessments of curdlan-doped smart nanocomposites containing erlotinib HCl

H Bera, YF Abbasi, V Gajbhiye, LL Ping, R Salve… - International journal of …, 2021 - Elsevier
… )-doped montmorillonite/poly(N-isopropylacrylamide-co-N,N′-methylene-bis-acrylamide)
[CN/MT/P(NIPA-co-MBA)] smart nanocomposites (NCs) were developed for efficient erlotinib

[HTML][HTML] Proton pump inhibitors reduce the survival of advanced lung cancer patients with therapy of gefitinib or erlotinib

CH Lee, MC Shen, MJ Tsai, JS Chang, YB Huang… - Scientific Reports, 2022 - nature.com
… After excluding ineligible patients, the remaining 5975 patients constituted our study cohort,
including 4340 in the gefitinib cohort and 1635 in the erlotinib cohort. The TKI cohorts were …

[PDF][PDF] In-silico molecular docking study of novel derivatives of erlotinib in glioma

D Tripathi, S Imran - Asia-Pac J Mol Biol Biotechnol, 2020 - academia.edu
… To see the binding mode of deferent classes of erlotinib carefully … study, we successfully
docked EFGR protein with erlotinib derivatives to give new insight for drug interaction study