[HTML][HTML] Optimal sequence of LT for symptomatic BM in EGFR-mutant NSCLC: a comparative study of first-line EGFR-TKIs with/without upfront LT
L Niu, H Wu, R Gao, L Chen, J Wang, H Duan… - Journal of Cancer …, 2024 - Springer
… This study seeks to obtain data which will help explore the optimal sequence of LT for
symptomatic BM … Based on the inclusion criteria, a total of 87 patients were included in this study. …
symptomatic BM … Based on the inclusion criteria, a total of 87 patients were included in this study. …
[PDF][PDF] A Randomized Phase II Study of Schedule-Modulated Concomitant Pemetrexed (Alimta®) and Erlotinib (Tarceva®) vs Single Agent Pemetrexed (Alimta®) in …
DR Gandara, B Piperdi, WV Walsh - classic.clinicaltrials.gov
… erlotinib in the control arm (Arm A) in the current study. We intend to explore the clinical
benefit of sequential pemetrexed and erlotinib … the extended study of single agent erlotinib. We …
benefit of sequential pemetrexed and erlotinib … the extended study of single agent erlotinib. We …
Impact of pharmacist's intervention on decreasing erlotinib interactions in the treatment of lung cancer patients in low resource settings
T Kovacevic, SV Kovacevic, M Stanetic… - Journal of Oncology …, 2021 - journals.sagepub.com
… this study have potential to decrease erlotinib serum … studied patients with detected erlotinib
interactions, we found that a third of them had one PPI, pantoprazole. Interaction of erlotinib …
interactions, we found that a third of them had one PPI, pantoprazole. Interaction of erlotinib …
[HTML][HTML] Epidemiological and clinical burden of EGFR Exon 20 insertion in advanced non-small cell lung cancer: A systematic literature review
H Burnett, H Emich, C Carroll, N Stapleton… - PLoS …, 2021 - journals.plos.org
… this study received chemotherapy followed by erlotinib, whereas most other studies evaluated
… There was a limited number of comparative studies investigating the efficacy and safety of …
… There was a limited number of comparative studies investigating the efficacy and safety of …
Preparation, Characterization and In-Vitro Evaluation of Erlotinib Gellan Beads.
S SUKUMAR, S AROCKIASAMY… - International Journal …, 2021 - search.ebscohost.com
… In the present study erlotinib-loaded gellan gum beads were prepared. The SEM image of
the beads revealed a spherical shape. The functional groups of beads were identified using …
the beads revealed a spherical shape. The functional groups of beads were identified using …
Efficacy and safety of first-line therapies in EGFR-mutated advanced non-small-cell lung cancer: a network meta-analysis
K Haeussler, X Wang, KB Winfree, Y D'yachkova… - Future …, 2022 - Future Medicine
… Additional networks were created for the sensitivity analyses (erlotinib and gefitinib as separate
nodes with erlotinib defined as the reference treatment). Networks for subgroup analyses …
nodes with erlotinib defined as the reference treatment). Networks for subgroup analyses …
[PDF][PDF] MOLECULAR DOCKING AND IN-SILICO ADME STUDIES OF NOVEL DERIVATIVE OF ERLOTINIB IN GLIOMA
D Tripathi, S Imran - researchgate.net
… the best drug candidate from Erlotinib, a renowned anti-cancer agent, derivatives. A total
of 200 structures were selected for the 2D crystal structure of erlotinib based on molecular …
of 200 structures were selected for the 2D crystal structure of erlotinib based on molecular …
ACY-241, an HDAC6 inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by inducing autophagy
SJ Park, SH Joo, N Lee, WJ Jang, JH Seo… - Archives of Pharmacal …, 2021 - Springer
… study, we aimed to develop a therapy against erlotinib resistance. We observed that HDAC6
is overexpressed in erlotinib… is responsible for erlotinib resistance in pancreatic cancer cells. …
is overexpressed in erlotinib… is responsible for erlotinib resistance in pancreatic cancer cells. …
EGFR inhibition with erlotinib induces membrane accumulation of aquaporin-2 via PDK1 and RSK activation
… PKA-independent pathway activated by erlotinib, and that the phosphoinositide dependent
… for erlotinib-induced AQP2 activation. Using our LLC-AQP2 cell model, we show that erlotinib-…
… for erlotinib-induced AQP2 activation. Using our LLC-AQP2 cell model, we show that erlotinib-…
Central composite design augmented quality-by-design-based systematic formulation of erlotinib hydrochloride-loaded chitosan-poly (lactic-co-glycolic acid) …
… Aim: This study aimed to formulate erlotinib hydrochloride (ERT-HCL)-loaded chitosan (CS)
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …