[HTML][HTML] Optimal sequence of LT for symptomatic BM in EGFR-mutant NSCLC: a comparative study of first-line EGFR-TKIs with/without upfront LT

L Niu, H Wu, R Gao, L Chen, J Wang, H Duan… - Journal of Cancer …, 2024 - Springer
… This study seeks to obtain data which will help explore the optimal sequence of LT for
symptomatic BM … Based on the inclusion criteria, a total of 87 patients were included in this study. …

[PDF][PDF] A Randomized Phase II Study of Schedule-Modulated Concomitant Pemetrexed (Alimta®) and Erlotinib (Tarceva®) vs Single Agent Pemetrexed (Alimta®) in …

DR Gandara, B Piperdi, WV Walsh - classic.clinicaltrials.gov
erlotinib in the control arm (Arm A) in the current study. We intend to explore the clinical
benefit of sequential pemetrexed and erlotinib … the extended study of single agent erlotinib. We …

Impact of pharmacist's intervention on decreasing erlotinib interactions in the treatment of lung cancer patients in low resource settings

T Kovacevic, SV Kovacevic, M Stanetic… - Journal of Oncology …, 2021 - journals.sagepub.com
… this study have potential to decrease erlotinib serum … studied patients with detected erlotinib
interactions, we found that a third of them had one PPI, pantoprazole. Interaction of erlotinib

[HTML][HTML] Epidemiological and clinical burden of EGFR Exon 20 insertion in advanced non-small cell lung cancer: A systematic literature review

H Burnett, H Emich, C Carroll, N Stapleton… - PLoS …, 2021 - journals.plos.org
… this study received chemotherapy followed by erlotinib, whereas most other studies evaluated
… There was a limited number of comparative studies investigating the efficacy and safety of …

Preparation, Characterization and In-Vitro Evaluation of Erlotinib Gellan Beads.

S SUKUMAR, S AROCKIASAMY… - International Journal …, 2021 - search.ebscohost.com
… In the present study erlotinib-loaded gellan gum beads were prepared. The SEM image of
the beads revealed a spherical shape. The functional groups of beads were identified using …

Efficacy and safety of first-line therapies in EGFR-mutated advanced non-small-cell lung cancer: a network meta-analysis

K Haeussler, X Wang, KB Winfree, Y D'yachkova… - Future …, 2022 - Future Medicine
… Additional networks were created for the sensitivity analyses (erlotinib and gefitinib as separate
nodes with erlotinib defined as the reference treatment). Networks for subgroup analyses …

[PDF][PDF] MOLECULAR DOCKING AND IN-SILICO ADME STUDIES OF NOVEL DERIVATIVE OF ERLOTINIB IN GLIOMA

D Tripathi, S Imran - researchgate.net
… the best drug candidate from Erlotinib, a renowned anti-cancer agent, derivatives. A total
of 200 structures were selected for the 2D crystal structure of erlotinib based on molecular …

ACY-241, an HDAC6 inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by inducing autophagy

SJ Park, SH Joo, N Lee, WJ Jang, JH Seo… - Archives of Pharmacal …, 2021 - Springer
study, we aimed to develop a therapy against erlotinib resistance. We observed that HDAC6
is overexpressed in erlotinib… is responsible for erlotinib resistance in pancreatic cancer cells. …

EGFR inhibition with erlotinib induces membrane accumulation of aquaporin-2 via PDK1 and RSK activation

R Babicz, R Bouley, P Cheung, N Baylor… - …, 2024 - journals.physiology.org
… PKA-independent pathway activated by erlotinib, and that the phosphoinositide dependent
… for erlotinib-induced AQP2 activation. Using our LLC-AQP2 cell model, we show that erlotinib-…

Central composite design augmented quality-by-design-based systematic formulation of erlotinib hydrochloride-loaded chitosan-poly (lactic-co-glycolic acid) …

HP Nijhawan, B Prabhakar, KS Yadav - Therapeutic Delivery, 2024 - Taylor & Francis
… Aim: This study aimed to formulate erlotinib hydrochloride (ERT-HCL)-loaded chitosan (CS)
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …