ACY-241, an HDAC6 inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by inducing autophagy
SJ Park, SH Joo, N Lee, WJ Jang, JH Seo… - Archives of Pharmacal …, 2021 - Springer
… study, we aimed to develop a therapy against erlotinib resistance. We observed that HDAC6
is overexpressed in erlotinib… is responsible for erlotinib resistance in pancreatic cancer cells. …
is overexpressed in erlotinib… is responsible for erlotinib resistance in pancreatic cancer cells. …
[HTML][HTML] Erlotinib and garcinia cambogia prevent adenine induced nephrotoxicity in adult male albino rats through modulating ekr1/2, stat3, and p53 apoptotic …
DM Amin, NM Halloull, WE Omar… - Adv. Anim. Vet …, 2023 - researcherslinks.com
… Aims: The purpose of this study was to evaluate how erlotinib and garcinia cambogia alleviate
the harmful effects of adenine on the rat’s kidneys. Methods: Forty animals were divided …
the harmful effects of adenine on the rat’s kidneys. Methods: Forty animals were divided …
Central composite design augmented quality-by-design-based systematic formulation of erlotinib hydrochloride-loaded chitosan-poly (lactic-co-glycolic acid) …
… Aim: This study aimed to formulate erlotinib hydrochloride (ERT-HCL)-loaded chitosan (CS)
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …
Lack of correlation between MET and PD-L1 expression in non-small cell lung cancer revealed by comparative study of matched biopsies and surgical resection …
M Ilié, V Hofman, C Bontoux, S Goffinet, J Benzaquen… - Lung Cancer, 2023 - Elsevier
… To address this gap, we conducted a comparative study of matched biopsies and surgical
… Our study reveals a lack of correlation between PD-L1 and MET expression in NSCLC …
… Our study reveals a lack of correlation between PD-L1 and MET expression in NSCLC …
Co-delivery of erlotinib and doxorubicin by MoS2 nanosheets for synergetic photothermal chemotherapy of cancer
J Liu, J Zheng, H Nie, H Chen, B Li, L Jia - Chemical Engineering Journal, 2020 - Elsevier
… Erlotinib was connected to MoS 2 via click chemistry with PEG as a linker. … The results
of this study demonstrate the excellent antitumor effect of MoS 2 -PEG-Er/DOX, providing a …
of this study demonstrate the excellent antitumor effect of MoS 2 -PEG-Er/DOX, providing a …
Downregulation of Thymidine Phosphorylase Expression by 17-AAG Potentiates the Cytotoxic Effect of Tamoxifen and Erlotinib in Human Squamous Cell Carcinoma …
YW Ling, JC Ko, JC Chen, JM Hsieh, PY Tseng… - Downregulation of … - papers.ssrn.com
… this study is to elucidate whether Hsp90 inhibitor 17-AAG could enhance tamoxifen- and
erlotinib-… and cell growth inhibitory effects of tamoxifen and erlotinib in NSCLC cells, which were …
erlotinib-… and cell growth inhibitory effects of tamoxifen and erlotinib in NSCLC cells, which were …
Estimates of overall survival in patients with cancer receiving different treatment regimens: emulating hypothetical target trials in the Surveillance, Epidemiology, and …
LC Petito, X García-Albéniz, RW Logan… - JAMA network …, 2020 - jamanetwork.com
… of erlotinib vs no initiation of erlotinib in individuals receiving gemcitabine. All components
of the treatment strategy needed to be in place within a prespecified period (the grace period) …
of the treatment strategy needed to be in place within a prespecified period (the grace period) …
[HTML][HTML] Frequency of EGFR Mutations in Patients with Lung Adenocarcinoma: Comparative Study between Private and Public Healthcare Centers
RCJ Rafael - Archives of Clinical and Medical Case Reports, 2020 - fortuneonline.org
Purpose: The present study aims to describe the differences in the prevalence of EGFR
mutation of lung adenocarcinoma between private and public healthcare institutions. Methods: …
mutation of lung adenocarcinoma between private and public healthcare institutions. Methods: …
Novel Erlotinib–Chalcone Hybrids Diminish Resistance in Head and Neck Cancer by Inducing Multiple Cell Death Mechanisms
J Murányi, C Duró, B Gurbi, I Móra, A Varga… - International Journal of …, 2023 - mdpi.com
… success, we synthesized a series of novel erlotinib–chalcone molecular hybrids with 1,2,3-…
compared to the 1:1 combination of erlotinib and a reference chalcone. The clonogenic …
compared to the 1:1 combination of erlotinib and a reference chalcone. The clonogenic …
Comparative study on the efficacy and exposure of molecular target agents in non–small cell lung cancer PDX models with driver genetic alterations
H Jo, S Yagishita, Y Hayashi, S Ryu, M Suzuki… - Molecular Cancer …, 2022 - AACR
… CONSORT diagram and study design. The selection criteria for PDX used in this study are
… The selection criteria for PDX used in this study are shown in A. Of the 55 lung cancer PDXs…
… The selection criteria for PDX used in this study are shown in A. Of the 55 lung cancer PDXs…