Research advances on L-DOPA-induced dyskinesia: from animal models to human disease

X Chen, Y Wang, H Wu, C Cheng, W Le - Neurological Sciences, 2020 - Springer
… such rating scales by presenting specifics on the Non-Humannon-human primate dyskinesia
rating method, using a video-based scoring system, termed Quantitative Dyskinesia Scale (…

Dyskinesia and Parkinson's disease: animal model, drug targets, and agents in preclinical testing

V Cesaroni, F Blandini, S Cerri - Expert Opinion on Therapeutic …, 2022 - Taylor & Francis
… We have also carried out a literature review reporting the … a novel non-human primate
dyskinesia rating method, using … Although many objective rating scales have been developed to …

Models of hyperkinetic disorders in primates

E Bezard - Journal of Neuroscience Methods, 2020 - Elsevier
… in non-human primates. These disabling conditions include notably L-dopa-induced dyskinesia
in Parkinson’s disease, tardive dyskinesia… other conditions presented in this short review, …

Dopamine D3 receptor ligand suppresses the expression of levodopa-induced dyskinesia in nonhuman primate model of parkinson's disease

T Oh, ES Daadi, J Kim, EW Daadi, PJ Chen… - Experimental …, 2022 - Elsevier
… To measure dyskinesia we used Dyskinesia disability rating scale that is scored for different
… A) & C) Quantitative analysis of sleep quality parameters showed that dyskinetic marmosets …

[HTML][HTML] Transient dystonia correlates with parkinsonism after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in non-human primates

SA Norris, L Tian, EL Williams, JS Perlmutter - Dystonia, 2023 - frontierspartnerships.org
… treatment status rated each video clip, which was presented in a … Prior to data analysis, we
conservatively defined the … ) since the scores on these two rating scales clearly diverged as …

[HTML][HTML] Intraventricular dopamine infusion alleviates motor symptoms in a primate model of Parkinson's disease

C Moreau, AS Rolland, E Pioli, Q Li, P Odou… - Neurobiology of …, 2020 - Elsevier
… the right frontal horn of 8 non-human primates treated with 1-methyl… , baseline PD score and
dyskinesia score under an acute … Y11 presented with transient vomiting at the dose of 40 mg, …

7-Nitroindazole reduces L-DOPA-induced dyskinesias in non-human Parkinsonian primate

MT Herrero, JE Yuste, L Cuenca-Bermejo… - Open …, 2023 - royalsocietypublishing.org
non-human primates. Although the study in rodents is relevant, it must be taken into account
that dyskinesias in non-human primatesAnalysis of the AUC, which encompasses both the …

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

ME Caulfield, JA Stancati, K Steece-Collier - JoVE (Journal of Visualized …, 2021 - jove.com
… /AIMs scoring data, created using rating scales for assigning … protocol presented here is
specifically helpful for larger-scale … practices assessing LIDs in non-human primates (NHPs), the …

[HTML][HTML] Impaired hand dexterity function in a non-human primate model with chronic Parkinson's disease

J Seo, J Won, K Kim, J Park, HG Yeo… - Experimental …, 2020 - ncbi.nlm.nih.gov
… (NHP) models with PD play an essential role in the analysis of … Traditional rating scales
previously used in the evaluation of … Introduction of the hand dexterity task (HDT) for cynomolgus …

[HTML][HTML] GLP-1 and GIP receptor agonists in the treatment of Parkinson's disease: translational systematic review and meta-analysis protocol of clinical and preclinical …

C Vaccari, D Grotto, TV Pereira, JLV de Camargo… - PloS one, 2021 - journals.plos.org
… Preclinical rodent or non-human primate studies and randomized … Quality of life rated by
validated scales or questionnaires, … with motor fluctuations and dyskinesias that have a serious …