… such as squalene synthase, farnesyl diphosphate synthase, fatty acid synthase, acetyl …
cell-based luciferase reporter assay that involved reporter constructs containing progressive …

… of maize squalene synthase impacted … squalene synthase expression in guayule by RNAi
technology, such that the pool of FPP might be available to enhance natural rubber synthesis (…

… -driven reporter, to facilitate the screening, the reporter could also … The in vitro, TR-FRET
based binding screen identified … Such a cooperative binding mode was also observed between …

… Here, we identified ERG28 (chromosome 14 open reading … , as a player in mammalian
cholesterol synthesis. ERG28 is … most cholesterol synthesis enzymes, as well as identifying sterol-…

… activity displayed by RORγ in reporter gene assays with mammalian cells in the absence
of an exogenous ligand supported the notion that RORγ may act as a constitutive activator …

… This includes FDFT1 which encodes squalene synthase (SQS), a protein … -inhibition has
been explored in preclinical studies demonstrating cooperation between SQS-inhibitors and …

… transferase inhibitors, farnesyltransferase inhibitors and squalene synthase inhibitors are
all … Unlike statin drugs, squalene synthase inhibitors do not inhibit the upstream steps of the …

… Here, a transcriptomics analysis of xiangfei nuts after harvest identified 156 genes
associated with the terpenoid metabolic pathway. A geranyl diphosphate (GPP) synthase (TgGPPS) …

… that these lipids function cooperatively. Comprehensive analysis … of ERG9 encoding squalene
synthase located in the middle … the deletion of ERG6 when a reporter gene plasmid, which …

… SmGAPC, SmRAS, SmDXS2, SmGGPPS1, SmCPS1, SmERF6, and SmERF115 promoters
drive the LUC gene to form a reporter, and SmMYB36 was overexpressed as an effector in …