A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
… The organ-on-a-chip (OoC) is an intriguing scientific and technological development in
which biology is coupled with microtechnology 1,2 to mimic key aspects of human physiology. …

Developer's guide to an organ-on-chip model

J Rogal, K Schlünder, P Loskill - ACS Biomaterials Science & …, 2022 - ACS Publications
… (6−12) In this perspective, we strive to provide a conceptual, stepwise guide (Figure 1) for
the holistic development of an organ-on-chip model, summarizing some of the key learnings …

Microfluidic organ-on-a-chip: a guide to biomaterial choice and fabrication

UMN Cao, Y Zhang, J Chen, D Sayson, S Pillai… - International journal of …, 2023 - mdpi.com
Organ-on-A-chip (OoAC) devices are miniaturized, functional, in vitro constructs that aim to
recapitulate the in vivo physiology of an organ using different cell types and extracellular …

Academic user view: organ-on-a-chip technology

M Busek, A Aizenshtadt, M Amirola-Martinez, L Delon… - Biosensors, 2022 - mdpi.com
Organ-on-a-Chip (OoC) systems bring together cell biology, … This perspective serves as a
guide for researchers in the … , gave rise to a whole new field—organ-on-a-chip (OoC)—which is …

Engineering organ-on-a-chip to accelerate translational research

J Ko, D Park, S Lee, B Gumuscu, NL Jeon - Micromachines, 2022 - mdpi.com
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-chip
technology is a form of microengineered cell culture platform that elaborates the in-vivo …

Clamping strategies for organ-on-a-chip devices

DJ Teixeira Carvalho, L Moroni… - Nature Reviews Materials, 2023 - nature.com
… The microphysiological organ-on-a-chip (OoC) has emerged as an alternative in vitro platform
to tackle shortcomings of existing preclinical models. OoCs claim to generate controllable …

Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications

LA Milton, MS Viglione, LJY Ong, GP Nordin, YC Toh - Lab on a Chip, 2023 - pubs.rsc.org
… In all, we aim to form a guide for the end-user to facilitate the in-house generation of 3D …
Many others have generated PDMS organ-on-a-chip devices like the lung-on-a-chip with …

Organ-on-a-chip: Current gaps and future directions

PL Candarlioglu, G Dal Negro, D Hughes… - Biochemical Society …, 2022 - portlandpress.com
… A similar network in UK, Organ-On-a-Chip Technologies Network, is aimed to nurture and
expand the OoC research by facilitating academic and industry interaction [20]. Many other …

[HTML][HTML] iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies

VEJM Palasantzas, I Tamargo-Rubio, K Le, J Slager… - Trends in Genetics, 2023 - cell.com
… to generate patient-specific PSC lines, differentiate them into diverse cell types, and seed
and combine them on microfluidic chips, have led to the establishment of organ-on-a-chip (OoC…

Comprehensive development in organ-on-a-chip technology

X Joseph, V Akhil, A Arathi, PV Mohanan - Journal of Pharmaceutical …, 2022 - Elsevier
Organ-on-a-chip (OOC) is an interdisciplinary technology that evolved as a contemporary
in … This review outlines the comprehensive development in the organ-on-a-chip technology, …