[HTML][HTML] Admixture mapping identifies genetic regions associated with blood pressure phenotypes in African Americans

Z Liu, D Shriner, NF Hansen, CN Rotimi, JC Mullikin… - PloS one, 2020 - journals.plos.org
disease risk, we employed admixture mapping to identify genetic loci with excess local African
… To identify SNPs that accounted for association signals discovered by admixture mapping

[HTML][HTML] The role of genetic ancestry as a risk factor for primary open-angle glaucoma in African Americans

BS Cole, HV Gudiseva, M Pistilli… - … & Visual Science, 2021 - iovs.arvojournals.org
… for the admixture mapping owing to a lack of significant findings in the discovery cohort. …
We hope that studying this admixed population will be helpful in mapping POAG genes with …

[HTML][HTML] Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans

N Nakatsuka, N Patterson, NA Patsopoulos… - Scientific reports, 2020 - nature.com
admixture mapping analysis led to the discovery of a genetic … to the chromosome 1 admixture
mapping peak. Nevertheless, … the admixture signal in 2007 and access to high-density new …

[HTML][HTML] Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35

S Cullina, GL Wojcik, R Shemirani, D Klarin… - … in Genetics, 2023 - frontiersin.org
… cardiovascular disease, affecting ∼8 million Americans, and is … a significantly higher
prevalence in African Americans (AAs) … genomic discovery analysis using admixture mapping in …

[PDF][PDF] Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry

M Graff, AE Justice, KL Young, E Marouli… - The American Journal of …, 2021 - cell.com
… was tested assuming an additive genetic model with each … are based on the African American
discovery phase only (AA … illustrated from the African American discovery and replication …

[HTML][HTML] Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture

L Kachuri, ACY Mak, D Hu, C Eng, S Huntsman… - … genetics, 2023 - nature.com
… We performed eQTL mapping and identified eQTLs that were … This variant has been linked
to high-density lipoprotein (HDL… TWAS models for gene discovery in admixed populations, we …

[HTML][HTML] Genetic ancestry inference and its application for the genetic mapping of human diseases

E Suarez-Pajes, A Díaz-de Usera… - International journal of …, 2021 - mdpi.com
… for the discovery of genetic loci associated with diseases and traits, … genetic ancestry estimation
and discuss the use of admixture … performed an admixture mapping in African Americans, …

Using modern DNA to perform admixture mapping in African-Americans with and without Multiple Sclerosis

N Nakatsuka - Integrating Ancient and Modern DNA To Study …, 2020 - search.proquest.com
admixture mapping analysis led to the discovery of a genetic … to the chromosome 1 admixture
mapping peak. Nevertheless, … the admixture signal in 2007 and access to high-density new …

[PDF][PDF] Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease

HK Somineni, S Nagpal, S Venkateswaran… - The American Journal of …, 2021 - cell.com
… for inflammatory bowel disease are discovered at genome-… diverse African American
cohort to enhance fine-mapping of … due to varying degrees of admixture, we used the control …

Genome-wide admixture and association analysis identifies African ancestry–specific risk loci of eosinophilic esophagitis in African Americans

Y Gautam, J Caldwell, L Kottyan, M Chehade… - Journal of Allergy and …, 2023 - Elsevier
… In admixed populations, admixture mapping (AM) methods … Such high-density genome-wide
markers provide better … cohort and a complementary discovery of genetic risk loci of …