… , has been shown to regulate neuronal adhesion, neurite outgrowth … Among them, the highly
sulfated E unit (CS-E), composed of … midkine, is specifically inhibited by chondroitin sulfate E.…

… A possible pathway for the biosynthesis of the highly sulfated … increased nuclear β-catenin
levels; and β-catenin nuclear … CS-E inhibited specific molecular and biological outcomes of …

… highly sulfated CS- GAGs observed by day 7 post- MI. The inhibitory effects of CS- E on axon
outgrowth in certain neuronal … µL of the supernatant was adsorbed onto 15 mg alumina, …

… nonspecifically adsorb onto … neurons as a uniform substrate as opposed to electrostatic
molecular barriers. In addition, the immobilization of highly sulfated CS subtypes (CS-D and CS-E…

… ability of CS-E sulfation sequence to recruit specific growth … that FGF2 loaded on highly
sulfated Hep triggered greater … for analyzing other non-nuclear signaling markers, such as …

Chondroitin sulfate (CS) stands as a pivotal compound in dietary supplements for osteoarthritis
treatment, propelling significant interest in the biotechnological pursuit of environmentally …

… to HN-binding GF, particularly basic fibroblast growth factor (… that both GFs do not adsorb
to the sulfated polysaccharides … with exogenous highly sulfated CS-E (chondroitin sulfate-E) …

… The results showed that the CS-E 19-mer had a tight binding … In 2020, Meara et al. reported
that a highly sulfated hexose … GzmA targets nuclear proteins like histones and lamins for …

… ability to degrade the chondroitin sulfate proteoglycans of the … to more highly sulfated CS
GAGs such as CS-D and CS-E, … a new route to bypassing damaged neurons (relay)37. As one …

… We previously reported that alginate sulfate (AlgSulf), a GAG-mimetic, reduces the proliferation
… unaffected, indicating that both GFs do not adsorb to the sulfated polysaccharides layer. …