Renal revascularization attenuates myocardial mitochondrial damage and improves diastolic function in pigs with metabolic syndrome and renovascular hypertension

RA Farahani, S Yu, CM Ferguson, XY Zhu… - Journal of …, 2022 - Springer
… function by PTRA ameliorated myocardial mitochondrial damage and diastolic dysfunction …
that 4 weeks after technically successful renal revascularization, cardiomyocyte mitochondrial

[HTML][HTML] The mitochondrion: A promising target for kidney disease

C Tanriover, S Copur, D Ucku, AB Cakir, NB Hasbal… - Pharmaceutics, 2023 - mdpi.com
… the mitochondria to improve kidney function and kidney treatment. … inhibitors, antioxidants,
mitochondrial permeability transition … A mitochondrial permeability transition pore (mPTP) is …

The mitochondrial permeability transition pore: an evolving concept critical for cell life and death

G Morciano, N Naumova, P Koprowski… - Biological …, 2021 - Wiley Online Library
… an unspecific increase in permeability of the … kidney cell injury caused by mPTP opening
is provided by Bendavia, a mPTP inhibitor, which inhibits damage caused by revascularization

[HTML][HTML] Tubular mitochondrial dysfunction, oxidative stress, and progression of chronic kidney disease

M Fontecha-Barriuso, AM Lopez-Diaz… - Antioxidants, 2022 - mdpi.com
… production and mitochondrial permeability transition pore (… mitochondrial biogenesis and
improved kidney function after … artery stent revascularization, it increased peripheral venous …

[HTML][HTML] Physiopathology of the permeability transition pore: Molecular mechanisms in human pathology

M Bonora, S Patergnani, D Ramaccini, G Morciano… - Biomolecules, 2020 - mdpi.com
… opening of the mitochondrial permeability transition pore complex (… revascularization had
no effect on ST-segment resolution or cardiac enzymes and did not improve clinical outcome. …

Kidney intrinsic mechanisms as novel targets in renovascular hypertension

A Eirin, AR Chade, LO Lerman - Hypertension, 2024 - Am Heart Assoc
… A mitochondrial permeability transition pore inhibitor improves renal outcomes after
revascularization in … growth factor improves renal outcomes following revascularization. Am J …

Mitochondrial dysfunction and the AKI-to-CKD transition

M Jiang, M Bai, J Lei, Y Xie, S Xu… - … of Physiology-Renal …, 2020 - journals.physiology.org
… opening of mitochondrial permeability transition pores, loss of … or inhibit mitochondrial
permeability transition. By inhibiting … 4 wk after ischemia significantly improves renal fibrosis after

[HTML][HTML] Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis

R Zou, W Shi, J Qiu, N Zhou, N Du, H Zhou… - Cardiovascular …, 2022 - Springer
Revascularization of occluded coronary arteries is a standard therapeutic … inhibited, the
opening of mitochondrial permeability … suppressed the mitochondrial permeability transition pore (…

[HTML][HTML] Oxidative stress and ischemia/reperfusion injury in kidney transplantation: focus on ferroptosis, mitophagy and new antioxidants

S Granata, V Votrico, F Spadaccino, V Catalano… - Antioxidants, 2022 - mdpi.com
… of the mitochondrial permeability transition pores (mPTP) … renal artery stenosis undergoing
revascularization with … S by NaHS after ischemia improved recovery of kidney function …

Role of abnormal energy metabolism in the progression of chronic kidney disease and drug intervention

X Liu, H Du, Y Sun, L Shao - Renal failure, 2022 - Taylor & Francis
enhances ATP production to the kidney by improving renal … of the mitochondrial permeability
transition pore [Citation22]. The … to inhibit renal pyruvate dehydrogenase decline in AKI and …