The TIR-NBS-LRR protein CSA1 is required for autoimmune cell death in Arabidopsis pattern recognition co-receptor bak1 and bir3 mutants
S Schulze, L Yu, A Ehinger, D Kolb, SC Saile, M Stahl… - BioRxiv, 2021 - biorxiv.org
… CHS3 is a TNL with additional integrated domains (LIM (Lin-… Mec-3 domain) domain and
putative DA-1 protease domain) at … CHS3 are necessary for triggering autoimmune cell death in …
putative DA-1 protease domain) at … CHS3 are necessary for triggering autoimmune cell death in …
HSP90 contributes to chs3-2D-mediated autoimmunity
N Zhang - 2021 - open.library.ubc.ca
… A mutant CHS3 protein with TIR‐NB‐LRR‐LIM domains modulates growth, cell death and
freezing tolerance in a temperature‐dependent manner in Arabidopsis. The Plant Journal, 63(…
freezing tolerance in a temperature‐dependent manner in Arabidopsis. The Plant Journal, 63(…
[HTML][HTML] Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional cell-death regulatory modes
… (ID) with homology to regulatory domains, which is … two cell-death regulatory modes for
CHS3/CSA1 pairs. One is mediated by ID domain on clade 1 CHS3, and the other relies on CHS3…
CHS3/CSA1 pairs. One is mediated by ID domain on clade 1 CHS3, and the other relies on CHS3…
Characterization of the role of CSA1 in maintaining homeostasis of BAK1-BIR3 complexes and triggering autoimmune cell death
L Yu - 2024 - ub01.uni-tuebingen.de
… activity is important for TIRmediated cell death. Nicotinamide, … For example, TNL protein
CHS3 contains a LIM domain at its … mutation in csa1 can suppress bak1 bir3mediated cell death. …
CHS3 contains a LIM domain at its … mutation in csa1 can suppress bak1 bir3mediated cell death. …
[HTML][HTML] The Arabidopsis TIR-NBS-LRR protein CSA1 guards BAK1-BIR3 homeostasis and mediates convergence of pattern-and effector-induced immune responses
… cell death, but the direct mechanisms leading to such deregulation remains unclear. Here,
we found that the TIR-NBS-LRR protein … cell death in bak1-4 and bak1-4 bir3-2 mutants via …
we found that the TIR-NBS-LRR protein … cell death in bak1-4 and bak1-4 bir3-2 mutants via …
Paired plant immune CHS3-CSA1 receptor alleles form distinct hetero-oligomeric complexes
Y Yang, OJ Furzer, EP Fensterle, S Lin, Z Zheng… - Science, 2024 - science.org
… and clade 3, we made more mutations in CHS3 TIR BB-loops to assess cell death phenotype
and … We then used BN-PAGE assays to test whether BAK1 or BIR proteins modulate CHS3-…
and … We then used BN-PAGE assays to test whether BAK1 or BIR proteins modulate CHS3-…
[HTML][HTML] HSP90 Contributes to chs3-2D-Mediated Autoimmunity
… , Isl-1 and Mec-3 (LIM) domain at its C terminus. The gain-of-function mutant, chs3-2D, exhibiting
… (F) Quantification of Ha Noco2 conidia growth on the leaf surface of the mutant chs3-2D …
… (F) Quantification of Ha Noco2 conidia growth on the leaf surface of the mutant chs3-2D …
The BIR3 interactome revealed the NLR CSA1 as a component necessary for BIR-and BAK1-mediated cell death
S Schulze - 2022 - ub01.uni-tuebingen.de
… N- and C-termini (TIR/CC and LRR) differ in the context of each … Additionally to that,
bir2-mutants reveal elevated cell death … the cell death occurring in bir2-mutants, double-mutants …
bir2-mutants reveal elevated cell death … the cell death occurring in bir2-mutants, double-mutants …
[HTML][HTML] The integrated LIM-peptidase domain of the CSA1-CHS3/DAR4 paired immune receptor detects changes in DA1 peptidase inhibitors in Arabidopsis
… domain swaps with several DA1 homologs, we show that the LIM-peptidase domain of the
family member CHS3/… mechanisms by which effectors modulate plant processes is enabling …
family member CHS3/… mechanisms by which effectors modulate plant processes is enabling …
[PDF][PDF] From Recognition to Susceptibility: Functional characterization of Plant-specific LIM-domain containing proteins in plant-microbe interactions
T Parkes - 2020 - researchportal.bath.ac.uk
… : The S8F mutation in WRR7 inhibits the cell death induced by the WRR7 autoimmune mutant
… Plant NLRs containing a TIR domain are collectively termed TIR-domain containing NLRs (…
… Plant NLRs containing a TIR domain are collectively termed TIR-domain containing NLRs (…