Use of epidermal growth factor receptor inhibitor erlotinib to treat palmoplantar keratoderma in patients with Olmsted syndrome caused by TRPV3 mutations

C Greco, S Leclerc-Mercier, S Chaumon… - JAMA …, 2020 - jamanetwork.com
mice had curled whiskers and a perm hair phenotype reminiscent of TGFA and EGFR
hypomorphic waved-1 and waved-2 mutants… years and profoundly depressed, had significant focal …

[图书][B] The Role of Epidermal Growth Factor Receptor Signaling in Hematopoietic Stem Cell Regeneration

T Fang - 2020 - search.proquest.com
… Whole-genome sequencing of HSPCs from irradiated EGF-treated mice … of mutation rate
compared to irradiated control mice, despite increased intergenic copy number variant mutations

The role of EGFR in vascular AT1R signaling: from cellular mechanisms to systemic relevance

M Gekle, V Dubourg, G Schwerdt, RA Benndorf… - Biochemical …, 2023 - Elsevier
… concerning cardiovascular epidermal growth factor receptor (… Deeper understanding of these
mechanisms is of importance … mice with a global hypoactive EGFR (Wa-2, mouse waved-2

[PDF][PDF] High epidermal growth factor concentration associated with somatic cell count in milk of cows with subclinical mastitis.

A Gokceoglu, GF Yarim, N Gultiken, M Yarim - 2020 - medycynawet.edu.pl
… The aim this study was to determine the milk epidermal growth factor (EGF) concentration
in … the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor

The emergent power of human cellular vs mouse models in translational hair research

AR Castro, C Portinha… - Stem Cells Translational …, 2022 - academic.oup.com
mutant mice have been routinely used in hair bioengineering approaches because: (i) nude
mice … been additionally included to physiologically resemble the human hair even deeper. In …

ERBB Receptors and Their Ligands in the Developing Mammary Glands of Different Species: Fifteen Characters in Search of an Author

A Morato, P Accornero, RC Hovey - Journal of mammary gland biology …, 2023 - Springer
… (ERBB) family of receptors and their ligands in mice (left), ruminants (middle) and humans (…
morphogenesis has not been clarified. The ERBB2/human epidermal growth factor receptor 2 …

In vivo modeling of the EGFR family in breast cancer progression and therapeutic approaches

AM Simond, WJ Muller - Advances in Cancer Research, 2020 - Elsevier
… the epidermal growth factor receptor (EGFR) family has been key to the development of
therapeutics and has … The Waved-2 expressing mice had impaired ErbB2-driven mammary tumor …

Regulation of the JAK2-STAT5 pathway by signaling molecules in the mammary gland

M Tian, Y Qi, X Zhang, Z Wu, J Chen, F Chen… - Frontiers in cell and …, 2020 - frontiersin.org
… Knockout of one allele of Akt2 in Akt1-deficient micereceptors, growth factors, inflammatory
cytokines, and integrins. ER, estrogen receptor; ERBB4, epidermal growth factor receptor 4; …

Effect of iRhom2 Cytotail Mutations on ADAM17 Function In Vivo: Implications for Tylosis with Oesophageal Cancer

AI Rabinowitsch - 2023 - search.proquest.com
skin and hair of homozygous iRhom2 cub or TOC mice is … those involved in the Epidermal
Growth Factor Receptor (EGFR) … To try to understand TOC on a deeper level, a mouse model …

p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer

P Miller, EH Akama-Garren, RP Owen… - Cell Death & …, 2023 - nature.com
… We crossed the KC and KC;iASPP Δ8/Δ8 mice with mice … H Top 5 transcription factors
represented by overlapping genes … that iASPP deletion has a more profound effect on the AP1 …