… We conclude that geopropolis is a natural product that exhibits anticancer properties that
should be further evaluated in monotherapy or polytherapy schemes to improve chemotherapy–…

… Geopropolis produced by stingless bees improved the effects of doxorubicin against HEp-2 …
, avoiding the side effects of chemotherapy, and exerting an immunomodulatory action. This …

… Previous findings from our group revealed that the combination of GEO with doxorubicin
led to a higher cytotoxic activity against tumor (HEp-2) cells and induced apoptosis [9]. While …

… Several biological activities of propolis and geopropolis have been … of chemotherapeutic
drugs. Propolis and … Together, data revealed the effects of geopropolis on different immune …

… chemotherapy drug doxorubicin. Propolis increased the expression of TLR-4, TNF-α, NF-κB,
and IL-10 in the monocytes exposed to doxorubicin. … -2 while simultaneously decreased the …

… An interesting study was carried out by Oliveira et al. to investigate the effect of geopropolis
… of doxorubicin and geopropolis inhibited autophagy in human monocytes through the …

… These works together with our study confirm the potential use of propolis as an … A new
chemotherapeutic approach using doxorubicin simultaneously with geopropolis favoring …

… Additionally, geopropolis increased the production of IL-10 in LPS-induced human monocytes
[[32]. The increase in the production of IL-10 has been observed in LPS stimulated human …

… The composition of geopropolis in phenolic compounds assessed using HPLC is abundant
… obtained for the rainy geopropolis propolis sample and the dry geopropolis sample, are …

… Using tools to optimise extraction methods, such as experimental design, central composite
rotational design (CCRD) can be an excellent alternative to obtain a rich extract in phenolic …