Genetic forms of frontotemporal lobar degeneration: current diagnostic approach and new directions in therapeutic strategies
L Sellami, D Saracino, I Le Ber - Revue neurologique, 2020 - Elsevier
… A pathological classification of FTLD is based on the … Four different subtypes of FTLD-TDP
(from A to D) have been … fifth subtype (FTLD-TDP type E) with distinctive pathological features …
(from A to D) have been … fifth subtype (FTLD-TDP type E) with distinctive pathological features …
Expanding the phenotype of frontotemporal lobar degeneration with FUS-positive pathology (FTLD-FUS)
K Chornenka, V Hirsch-Reinshagen… - … of Neuropathology & …, 2020 - academic.oup.com
… cause of frontotemporal dementia characterized by fused in sarcoma-positive inclusions.
It is classified as a subtype of frontotemporal lobar degeneration with FUS pathology. Cases …
It is classified as a subtype of frontotemporal lobar degeneration with FUS pathology. Cases …
Frontotemporal lobar degeneration
… with a specific pathology and subtypes of each pathology as well as … A less common pathology
is FTLD related to FUS–Ewing … is that each of these pathological entities tends to occur in …
is FTLD related to FUS–Ewing … is that each of these pathological entities tends to occur in …
Young-onset frontotemporal dementia with FUS pathology
M Gowell, I Baker, O Ansorge, M Husain - Practical Neurology, 2021 - pn.bmj.com
… These features led to a neuropathological diagnosis of frontotemporal lobar degeneration
… However, no mutations have yet been linked with the FTLD-FUS histological subtype (which …
… However, no mutations have yet been linked with the FTLD-FUS histological subtype (which …
Increase in wasteosomes (corpora amylacea) in frontotemporal lobar degeneration with specific detection of tau, TDP-43 and FUS pathology
R Alsina, M Riba, A Pérez-Millan… - Acta Neuropathologica …, 2024 - Springer
… been suggested that a UPS failure could be involved in the pathophysiology of the disease
[38, 49]. In … Analyzing FLTD subtypes, we observed that FTLD-FUS shows a more substantial …
[38, 49]. In … Analyzing FLTD subtypes, we observed that FTLD-FUS shows a more substantial …
Frontotemporal lobar degeneration TDP-43-immunoreactive pathological subtypes: clinical and mechanistic significance
… selective degeneration of the frontal and temporal lobes is a consistent feature and “frontotemporal
lobar degeneration” (FTLD) is used as the generic term for those pathologies that …
lobar degeneration” (FTLD) is used as the generic term for those pathologies that …
Distinct early symptoms in neuropathologically proven frontotemporal lobar degeneration
I Kawakami, T Arai, S Shinagawa… - … Journal of Geriatric …, 2021 - Wiley Online Library
… Frontotemporal lobar degeneration (FTLD) is associated with … ), or fused in sarcoma protein
(FUS). There have been very few … different clinical subtypes and pathological subtypes. This …
(FUS). There have been very few … different clinical subtypes and pathological subtypes. This …
Incidence of syndromes associated with frontotemporal lobar degeneration in 9 European countries
… PPA cases have AD as the underlying pathology. Moreover, patients in a prodromal stage …
FTLD subtypes. Incidence rates were computed as the ratio of the number of new FTLD cases …
FTLD subtypes. Incidence rates were computed as the ratio of the number of new FTLD cases …
Mixed neuropathology in frontotemporal lobar degeneration
C Pennington, L Marini, E Coulthard… - … and Frontotemporal …, 2020 - Taylor & Francis
… We reviewed the occurrences of mixed pathology in cases of … by detailed neuropathological
subtype (Citation2). It is well … , and in a further case FUS and tau pathology co-existed. LBD …
subtype (Citation2). It is well … , and in a further case FUS and tau pathology co-existed. LBD …
A case of frontotemporal lobar degeneration with FUS-positive pathology (FTLD-FET) with corticobasal features and language deficits
V Goodwill, D Coughlin, D Pizzo… - … of Neuropathology & …, 2021 - academic.oup.com
… Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of pathologies that …
, 5%–10% of FTLD cases have pathological cytoplasmic accumulation of fused in sarcoma (…
, 5%–10% of FTLD cases have pathological cytoplasmic accumulation of fused in sarcoma (…