… To test the regulatory effects of TWIST1 on miR-10a, we used a shRNA and OE lentivirus of
… of obtaining normal controls, this study collected only three cases of normal joint synovium in …

… capsule, the synovium consisting of fibroblast-like synoviocytes (FLS), macrophage-like …
molecular regulation of miRNA is of great value for the future development of novel therapeutic …

… homeostasis and joint remodeling by controlling fibroblast-like synoviocytes (FLSs),
chondrocytes… In the next sections, we will discuss how different miRNAs can regulate these …

… However, subsequent studies found that lncRNA could regulate target gene expression at
… down-regulated. Then, the expression of circ_0003353 in fibroblast-like synoviocytes was …

… Fibroblast-like synoviocytes (FLSs) are an important part of the synovial membrane which
… A novel NF-κB/YY1/microRNA-10a regulatory circuit in broblast-like synoviocytes regulates …

… Tissue inhibitors of MMPs (TIMPs), a physiologic inhibitor produced by synovium chondrocytes
and fibroblast cells, tightly regulate MMP gene expression in RASFs56. All TIMPs can …

… These results indicate a novel role for activated DDR- 2 in RA FLS, showing that DDR- 2 is
responsible for regulating the … DDR- 2 regulates the expression of IL- 15 and Dkk- 1 in RA …

… SMAD3 is a key factor that regulates the production of … We chose miRNAs, responsible
for regulating the gene … cell line (SW982) and in the fibroblast-like synoviocytes (FLSs) [27,28]. …

… controls were also collected in the present study. Blood samples of RA patients and controls
were … The demographic details of 306 RA patients and controls were given in Table 1. The …

… A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblastlike synoviocytes
regulates inflammation in rheumatoid arthritis. Sci Rep 2016; 6: 20059. https://doi.org/10.1038/ …