Understanding the Role of Connexins in Hepatocellular Carcinoma: Molecular and Prognostic Implications

SP Papadakos, E Chatzikalil, K Arvanitakis… - Cancers, 2024 - mdpi.com
… activity and the enhancement of connexin expression via the … the presence of which marks
transcriptional activity and nuclear … fatty liver disease (NAFLD), is a chronic liver disease with a …

[HTML][HTML] Role of connexin 32 in the directional differentiation of induced pluripotent stem cells into hepatocytes

Y Xu, Y Wang, R Qi, K Li, X Wang, X Li… - International Journal of …, 2024 - ncbi.nlm.nih.gov
… and enhanced the expression of the aforementioned hepatic … and AFP, exhibited marked
increases in the upregulated … , hepatitis, cirrhosis and hepatocellular carcinoma 43 . Most …

[PDF][PDF] Role of connexins, pannexins and their channels in liver cancer

K Leroy - 2023 - researchportal.vub.be
… (HCC), which often develops from chronic liver disease. Risk factors for the development of
… the Cx expression and functionality of gap junctions in liver cancer cell lines. Cell lines are …

A role of connexin 43 on the drug-induced liver, kidney, and gastrointestinal tract toxicity with associated signaling pathways

R Katturajan, SE Prince - Life sciences, 2021 - Elsevier
… consumption in cells, collectively say organ damage [20,21]. … the liver, numerous toxicants
are reported to have liver damagecell line, results in round-shaped loosely attached cells and …

Effects of connexin 32-mediated lung inflammation resolution during liver ischemia reperfusion

Z Zhang, W Yao, D Yuan, F Huang, Y Liu… - Digestive Diseases and …, 2020 - Springer
cell infiltration, remarkable pulmonary hemorrhage, marked … septal narrowing and focal
enlargement of the diameter of … whether connexins are potential novel therapeutic targets in …

Cholestasis differentially affects liver connexins

A Cooreman, R Van Campenhout… - International journal of …, 2020 - mdpi.com
liver of cholestatic mice and in human hepatoma HepaRG … Changes in connexin expression
in liver disease have been linked … Detection of the proteins was carried out using enhanced

Gap and tight junctions in liver: structure, function, and pathology

JW Murray, DC Spray - The Liver: Biology and Pathobiology, 2020 - Wiley Online Library
… of the liver and the gap junction protein, connexin 32, outside … cells is well maintained, as
evidenced by retention of labeled … has led to enhanced migration of multiple cell types in both …

Hepatic cell junctions: Pulling a double‐duty

R Van Campenhout, M Vinken - Liver International, 2024 - Wiley Online Library
… with enhanced claudin- 1 and occludin protein presence in … and connexin32 expression
levels in liver disease, while the … marks highly proliferative hematopoietic stem cells in human …

Dual-regulation by Cx32 in hepatocyte to trigger and worsen liver graft injury

F Huang, Z Deng, Q Zhang, Z Zhang, X Li, W Zeng… - Translational …, 2023 - Elsevier
… investigate the role of connexin32 (Cx32) in liver graft injury … DHE-labeled positive fluorescence
was determined for at … inhibited NOX4 with GKT137831 or enhanced Nrf2 with CDDO-EA…

Investigating the role of connexin 32 in breast cancer

D Uğur - 2020 - search.proquest.com
connexin signal levels in labeled cells were measured. It seems that upon Cx32 infection, in
Hs578T, Cx43 levels … In hepatocellular carcinoma cell line SMMC-7721 knockdown of Cx32 …