Molecular signatures of idiopathic pulmonary fibrosis
IR Konigsberg, R Borie, AD Walts… - American journal of …, 2021 - atsjournals.org
… Volcano plots depicting features that are statistically significant in idiopathic pulmonary
fibrosis (IPF) lung tissue compared with control lung tissue at a false discovery rate <0.05 (blue …
fibrosis (IPF) lung tissue compared with control lung tissue at a false discovery rate <0.05 (blue …
MicroRNA and protein-coding gene expression analysis in idiopathic pulmonary fibrosis yields novel biomarker signatures associated to survival
NG Casanova, T Zhou, ML Gonzalez-Garay… - Translational …, 2021 - Elsevier
… (miRNA) gene signatures as biomarkers in patients with Idiopathic pulmonary fibrosis (IPF), …
identify potential miRNA or gene signatures to serve as novel biomarkers for survival in IPF …
identify potential miRNA or gene signatures to serve as novel biomarkers for survival in IPF …
[HTML][HTML] A novel prognostic signature for idiopathic pulmonary fibrosis based on five-immune-related genes
L Qiu, G Gong, W Wu, N Li, Z Li, S Chen… - … of Translational …, 2021 - ncbi.nlm.nih.gov
… Therefore, we constructed a molecular genomic signature to predict the prognosis of IPF …
the performance of the genomic signature in the validation cohort. The signature showed an …
the performance of the genomic signature in the validation cohort. The signature showed an …
Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition with poor survival times. We
previously published a genome-… size estimates, we performed a genome-wide meta-analysis …
previously published a genome-… size estimates, we performed a genome-wide meta-analysis …
[HTML][HTML] Construction and validation of a novel prognostic signature of idiopathic pulmonary fibrosis by identifying subtypes based on genes related to 7 …
T Huang, WY He - Frontiers in Genetics, 2022 - frontiersin.org
… This study explores a novel potential clinical marker suitable for IPF by constructing a
prognostic signature. We focused on the role of m7GRGs in IPF and constructed a novel m7GPS …
prognostic signature. We focused on the role of m7GRGs in IPF and constructed a novel m7GPS …
Pan-transcriptome-based candidate therapeutic discovery for idiopathic pulmonary fibrosis
… nintedanib, for treatment of patients with idiopathic pulmonary fibrosis (IPF). However, neither
… minimal effect on IPF-specific gene signature or alter translational modifications involved in …
… minimal effect on IPF-specific gene signature or alter translational modifications involved in …
[HTML][HTML] Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis
P Sivakumar, R Ammar, JR Thompson, Y Luo… - Respiratory …, 2021 - Springer
… translational biomarker studies. Transcriptomic and proteomic disease signatures generated
from clinically relevant human … ” modeling can enable translational disease understanding, …
from clinically relevant human … ” modeling can enable translational disease understanding, …
Precision medicine in idiopathic pulmonary fibrosis therapy: From translational research to patient-centered care
KM Antoniou, E Tsitoura, E Vasarmidi… - Current Opinion in …, 2021 - Elsevier
… The pathogenic mechanisms leading to irreversible fibrosis are not fully understood;
however, advances in basic and translational research have identified new potential therapeutic …
however, advances in basic and translational research have identified new potential therapeutic …
Transcriptomic and epigenetic profiling of fibroblasts in idiopathic pulmonary fibrosis
A Hanmandlu, L Zhu, TCJ Mertens… - American Journal of …, 2022 - atsjournals.org
… highly fibrotic lung regions, yet the genetic signature from fibroblasts in areas of active …
novel genomic signature with translational significance for human idiopathic pulmonary fibrosis…
novel genomic signature with translational significance for human idiopathic pulmonary fibrosis…
Fibrometabolism—An emerging therapeutic frontier in pulmonary fibrosis
B Selvarajah, I Azuelos, D Anastasiou… - Science Signaling, 2021 - science.org
… of fibrosis, most notably in idiopathic pulmonary fibrosis (IPF), the most rapidly progressive
and fatal of all fibrotic … In terms of the potential translational importance of these findings, …
and fatal of all fibrotic … In terms of the potential translational importance of these findings, …