Real-world evaluation of the impact of radiotherapy and chemotherapy in elderly patients with glioblastoma based on age and performance status

KA Al Feghali, SM Buszek, H Elhalawani… - Neuro-Oncology …, 2021 - academic.oup.com
… Briefly, of 204 705 patients included in the NCDB glioma database, 48 919 … recent Canadian
prospective trial, 13 in which the addition of TMZ to short-course RT in elderly patients with …

[HTML][HTML] Prognostic and predictive factors in elderly patients with glioblastoma: a single-center retrospective study

J Liu, C Li, Y Wang, P Ji, S Guo, Y Zhai… - Frontiers in Aging …, 2022 - frontiersin.org
… of elderly patients with GBM who were treated by a single medical team, which suggests that
this study has … High Grade Glioma treatment in elderly people: is it different than in younger …

Management of glioblastomas in the elderly population

F Laigle-Donadey, S Greffard - Revue Neurologique, 2020 - Elsevier
… by temozolomide in older patients suffering from malignant gliomas with … prospective
studies, radiotherapy has now found its place in the standard of care of gliomas of elderly patients

Retrospective single-center study on elderly patients with glioblastoma between 2014 and 2018 evaluating the effect of age and performance status on survival

JM Pirkkalainen, AS Jääskeläinen… - Neuro-Oncology …, 2022 - academic.oup.com
… over 65 years at the time of diagnosis, with malignant glioma … in longer survival than
short-course radiotherapy alone (9.3 … In their prospective study containing 100 patients with GBM …

[HTML][HTML] Update on the management of elderly patients with glioblastoma: a narrative review

SA Ironside, A Sahgal, J Detsky, S Das… - Annals of Palliative …, 2021 - apm.amegroups.org
… ultra-short course radiation course is needed as patients should be … elderly patients with
glioblastoma treated with concurrent and adjuvant TMZ during short-course radiation therapy

Determining the optimal adjuvant therapy for improving survival in elderly patients with glioblastoma: a systematic review and network meta-analysis

F Nassiri, S Taslimi, JZ Wang, JH Badhiwala… - … cancer research, 2020 - AACR
… regimens studied provided similar treatment benefits in older patients with GBM. … future
studies are warranted to similarly focus on the role of these novel approaches in older patients

Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients

SA Climans, AA Brandes, JG Cairncross, K Ding… - Journal of neuro …, 2020 - Springer
… There have been prospective trials in low grade glioma in … this large randomized trial of
short-course radiotherapy with or … There are unique considerations for elderly patients with …

[PDF][PDF] … UTILIZATION AND REDUCED MEDICARE SPENDING OF SHORT-COURSE RADIATION THERAPY FOR PRIMARY CNS TUMORS IN ELDERLY ADULTS

K Tringale, A Miller, K Beal, J Yang, L Pike… - Neuro …, 2022 - researchgate.net
… : For elderly/frail glioma patients, shortening radiotherapy from 6 to 3 weeks (short-course RT
[SC… II or IDH mutant grade III glioma and indications for radiation therapy were enrolled in a …

Survey of treatment recommendations for elderly patients with glioblastoma

MA Vaz Salgado, J Torres, J Esteban… - Clinical and …, 2020 - Springer
… conclusively since some randomized trials have shown similar outcomes comparing
short course radiation (35–40 Gy) with long course radiation (60 Gy in 30 fractions) [7, 8]. …

Cost Minimization Analysis of Conventional vs. Short-Course Radiotherapy with Temozolomide for Non-Elderly Patients with Newly Diagnosed Glioblastoma

J Hill, SI Patel, YM Zhu, TM Steed… - International Journal of …, 2022 - redjournal.org
… For patients with newly diagnosed glioblastoma, short-course RT with TMZ leads to cost …
Short-course RT with TMZ also reduces the number of treatment slots needed for these patients, …