… to short-course radiotherapy leads to better survival outcomes of elderly patients with GBM
[35]. … While ongoing trials are showing some promise, future studies are warranted to better …

… However, these studies did not compare clinical outcome in older patients. … This study can
serve as a pilot for data building the reasoning for further prospective studies with larger study …

… Prospective studies could be warranted. … The authors concluded that in elderly patients
over 70 years, both TMZ … of elderly and/or frail patients affected by high-grade gliomas treated …

… routine management of newly diagnosed malignant glioma. … We found 1 randomized
prospective trial that did not find any … , and short-course RT of 34 Gy for 10 days in elderly patients (…

… High-grade gliomas account for more than 70% of all malignancies of the central nervous …
) A prospective study of short-course radiotherapy in poor prognosis glioblastoma multiforme. …

… is found in about 50% of malignant gliomas (27). EGFR … elderly patients may receive HFRT
alone or temozolomide alone in cases in which the tumor is MGMT methylated. Future studies …

… study regarding the use of bevacizumab in GBM patients, no … detected between elderly and
non-elderly patients. Nevertheless… A prospective study integrating a geriatric assessment and …

… no prospective study with elderly IDHm patients, and the available retrospective studies are
… [30] reported the feasibility and the efficacy of the combination of short-course radiotherapy (…

… protocols versus short-course radiotherapy without chemotherapy. … , further prospective
studies are needed to con rm our nding. … treatment options offered to elderly patients with GBM at …

… information used for potential future research purposes. All … patients undergoing the first
craniotomy for malignant glioma suffered a postoperative complication. Previous research …