Biological function and molecular mechanism of SRSF3 in cancer and beyond

J Xiong, Y Chen, W Wang, J Sun - Oncology Letters, 2022 - spandidos-publications.com
… During splicing, the serine/arginine-rich domain (RS) of the … binding protein (PTBP) 1 and
PTBP2 bind to exonic splicingbinding protein microtubule associated protein RP/EB family

Pre-mRNA splicing and its cotranscriptional connections

H Shenasa, DL Bentley - Trends in Genetics, 2023 - cell.com
… cotranscriptional binding to exonic and intronic splicing … and indirect contacts mediated by
a network of SR proteins [ … Putative protein:protein contacts between Pol II and splicing factors

USP15 and USP4 facilitate lung cancer cell proliferation by regulating the alternative splicing of SRSF1

T Das, EY Lee, HJ You, EEK Kim, EJ Song - Cell Death Discovery, 2022 - nature.com
splicing factor 1 (SRSF1), also known as pre-mRNA-splicing factor ASF1/SF2 is the archetype
member of the SR family … tumor-suppressor activity due to reduced binding with MYC [44]. …

A quantitative RT-PCR assay to monitor luciferase reporter mRNA levels

R Thomas - 2022 - escholarship.org
SR proteins belong to the serine/arginine family and recognize both exonic splice enhancers
(ESEs) and intronic splice … This relaxes the ring structure of the Balbiani transcript allowing …

Imaging organization of RNA processing within the nucleus

J Biswas, W Li, RH Singer… - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
… increased loading of splicing factors but not RNA Pol II and reversed by splicing inhibition. …
RNA-binding proteins also can dictate alternative splicing changes, not only by competing …

[图书][B] Regulation and Modulation of Alternative Splicing Outcomes by RNA Binding Proteins

JA Ellis - 2023 - search.proquest.com
… To all my family, friends, and lab members for being an essential part of … proteins bind to
the expanded CCUG RNA repeats found in DM2, suggesting that these two splicing factors

[图书][B] The Impact of Mutations and Downmodulation of LUC7L2 and Other Splicing Factors on Alternative Splicing Landscapes in Leukemic Cells and Malignant …

CE Hershberger - 2020 - search.proquest.com
family of proteins are the orthologs of yeast splicing factor Luc7p, little is known about their
function in splicing. … SR proteins frequently recognize and bind to exonic sequences, and most …

Body temperature and the minor spliceosome control disease-associated and tissue-specific alternative splicing and gene expression

S Meinke - 2020 - refubium.fu-berlin.de
… U1 snRNP to the 5’ splice site, binding of splicing factor 1 (SF1) to the … -studied families of
splicing regulators are the SR proteins … by both direct binding to specific exonic regions and by …

Characterising (pre-) mrnp organisation at different stages of gene regulation using single-molecule microscopy

S Adivarahan - 2021 - papyrus.bib.umontreal.ca
… the SR protein family, all of which share the characteristic RS … or two RNA-binding domains
and are known to bind to specific … exonic splicing enhancers (ESEs), typically occupied by SR

The cap-binding complex CBC and the eukaryotic translation factor eIF4E: co-conspirators in cap-dependent RNA maturation and translation

JC Mars, M Ghram, B Culjkovic-Kraljacic, KLB Borden - Cancers, 2021 - mdpi.com
… RAM, a small protein co-factor, binds RNMT and increases … About 95% of multi-exonic genes
undergo AS [59]. AS events … and not via interactions with splice factors or UsnRNA as seen …