… of studies investigated GxE interactions with PM 2.5 (… risk factor for cardiovascular disease
and mortality [3]. Black carbon and NO 2 were the next most commonly investigated pollutants. …

… Both genetic factors and air pollution are risk factors for coronary artery … We explored the
separate, combined effect or interaction association among genetic factors, air pollution and …

… interactions for CVD have mostly been identified for smoking and coronary artery disease
(CAD) or related risk factors… By comparison, there is more limited evidence for GxE interactions …

… air pollution and genetic risk factors with hypertension and explore the interactions between
air pollution and genetic risk. … Hypertension is a major risk factor for cardiovascular diseases (…

… the gene × PM exposure interaction on blood pressure levels … linking air pollution and adverse
cardiovascular outcomes. … As a prominent risk factor of multiple cardiovascular diseases, …

… with a wide range of cardiovascular diseases and even death (… the interactions of genetic
factors and air pollutants exposure … , which is an important risk factor for cardiac arrhythmias (4, …

… analysis described above, we fitted two-pollutant models by adjusting for one of O 3 , NO 2
and SO 2 . In the second stage, we introduced an interaction … with coronary artery disease. …

… pollution as a modifiable risk factor, providing evidence of its association with cardiovascular
risk factors … For example, a study explored the interaction between air pollution and genetic …

… risk factors might interact with CAD risk. Several studies investigated whether the CAD risk
alteration associated with air pollution … also reported the interaction between air pollution and …

… for the effects of air pollutants and gene by air pollutants interactions on blood lipid levels. …
cardiovascular disease history, although we have carefully adjusted for medication history. …