[HTML][HTML] … benefits of first-line treatments for Asian patients with advanced EGFR-mutated NSCLC harboring L858R mutation: a systematic review and network meta …

SK Chan, HCW Choi, VHF Lee - JTO Clinical and Research Reports, 2022 - Elsevier
… , erlotinib plus bevacizumab and gefitinib plus pemetrexed-based chemotherapy). Asian
patients with L858R mutation had no significant OS benefits from all these treatments. …

[HTML][HTML] Afatinib as First-Line Treatment in Asian Patients with EGFR Mutation-Positive NSCLC: A Narrative Review of Real-World Evidence

S Lu, JY Shih, TW Jang, CK Liam, Y Yu - Advances in therapy, 2021 - Springer
gefitinib in real-world patients in Asia. Importantly, the efficacy and safety of afatinib is seen
in groups of Asian patients … brain metastases, and frail patients or those with other underlying …

[HTML][HTML] Overall survival benefits of first-line treatments for Asian patients with advanced epidermal growth factor receptor-mutated NSCLC harboring exon 19 deletion …

SK Chan, HCW Choi, VHF Lee - Cancers, 2022 - mdpi.com
… In addition, erlotinib and gefitinib were grouped in … Asian patients with 19del had no OS
benefits with all approved EGFR-TKIs and combination treatment, albeit significant PFS benefits. …

[HTML][HTML] Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non-small-cell lung cancer: A meta analysis

M Yi, T He, K Wang, Y Wei - Clinics, 2023 - SciELO Brasil
… monotherapy in East Asian patients with locally advanced or … gefitinib maintenance therapy
versus gefitinib mono-therapy in East Asian patients with locally advanced or metastatic non

Furmonertinib (AST2818) versus gefitinib as first-line therapy for Chinese patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung …

Y Shi, G Chen, X Wang, Y Liu, L Wu, Y Hao… - The Lancet …, 2022 - thelancet.com
… furmonertinib was superior to gefitinib in terms of progression-free survival as first-line
treatment for Chinese patients with EGFR mutation-positive NSCLC. This benefit was consistent in …

[HTML][HTML] … safety of first-line treatments for of advanced EGFR mutation-positive non-small-cell lung cancer in Asian populations: a systematic review and network meta …

W Chen, J Miao, Y Wang, W Xing, X Xu… - Frontiers in …, 2023 - frontiersin.org
… In 2010, gefitinib (Gef) was examined as the first-line treatment for locally … in this review to
be the best treatment for all patients in the Asian population with locally advanced or metastatic …

[HTML][HTML] Comparing gefitinib and traditional chemotherapy for better survival in patients with non-small cell lung cancer: A systematic review

S Kanagalingam, ZU Haq, NV Srinivasan, AI Khan… - Cureus, 2023 - ncbi.nlm.nih.gov
… In this systematic review, we will compare the use of gefitinib … therapies, such as
gefitinib/lapatinib and gefitinib/pemetrexed … review and network meta-analysis revealed that Asian

Toxicity profile of epidermal growth factor receptor tyrosine kinase inhibitors for patients with lung cancer: A systematic review and network meta-analysis

Y Zhao, B Cheng, Z Chen, J Li, H Liang, Y Chen… - Critical Reviews in …, 2021 - Elsevier
… Of all included patients, 6458 (48.3 %) were female and 5429 (40.7 %) were non-Asian. The
… , and erlotinib and gefitinib for ALT elevation; but more toxic than gefitinib for neutropenia. …

Survival analysis for older patients with epidermal growth factor receptor mutation‐positive advanced nonsmall cell lung cancer after progression of first‐line gefitinib

X Nie, P Zhang, G Cheng, XN Wu… - Asia‐Pacific Journal of …, 2022 - Wiley Online Library
… For older patients with EGFR-mutant advanced NSCLC, EGFR … Survival benefit of
chemotherapy after failure of gefitinib … for older patients with EGFR-mutant advanced NSCLC who …

[HTML][HTML] The efficacy of first-line tyrosine kinase inhibitors combined with co-medications in Asian patients with EGFR mutation non-small cell lung cancer

VYF Su, KY Yang, TY Huang, CC Hsu, YM Chen… - Scientific reports, 2020 - nature.com
… A recent phase III, randomized, controlled trial 8 , (LUX-Lung 7), revealed that afatinib
exerted significant benefits in PFS compared to gefitinib in NSCLC patients with EGFR-activating …