… In addition, we saw no significant differences in lesion size, necrotic core size, macrophage
area, smooth muscle cell area, collagen area or calcification in the athero-prone aortic roots …

… atherosclerosis involves the development of fatty streaks upon the vascular wall that evolve
into lipid and macrophage rich necrotic … Low-density-lipoprotein (LDL)-rich macrophage and …

… Apart from the formation and enlargement of a central necrotic core, necrotic macrophages
… of plaque development, 39 suggesting that macrophage necroptosis plays a major role in …

… contribution of each death mode to the necrotic core formation during atherosclerosis
development. Although we found that lesional macrophages can die either through apoptosis or …

… a cell that shares morphological features with necrosis. The balance of RIPK1 signaling in
… macrophage necroptosis and the development of the necrotic core within the atherosclerotic …

… , other studies confirm that macrophage apoptosis positively regulates the development of
… reduced, and the number of programmed necrotic macrophages in the lesion was less than …

… , acute heart failure, and atherosclerosis, no compelling evidence is … /RIP3-mediated
necroptosis plays a critical role in developing … by mononuclear macrophage infiltration, necrosis of …

… atherosclerosis (AS), but the underlying mechanism is unclear. Since mitochondrial homeostasis
is emerging as a core player in the development of … (ROS), tumor necrosis factor-alpha (…

… To confirm that these observations were not specific for this particular MLKL targeting
sequence, we also examined the development of atherosclerosis with a distinct MLKL-targeting …

… on the role of RIP1 and RIP3-mediated macrophage necrosis in atherosclerosis. Research
… or Apoe−/−), macrophage necrosis can promote the development of the disease. But it was …