A novel therapeutic strategy for hepatocellular carcinoma: Immunomodulatory mechanisms of selenium and/or selenoproteins on a shift towards anti-cancer
BK Wu, QH Chen, D Pan, B Chang, LX Sang - International …, 2021 - Elsevier
… Selenium (Se) is an essential trace chemical element that is widely distributed worldwide. …
associated with many human diseases, including hepatocellular carcinoma (HCC). Recently, …
associated with many human diseases, including hepatocellular carcinoma (HCC). Recently, …
Molecular Mechanisms of the Therapeutic Effect of Selenium Nanoparticles in Hepatocellular Carcinoma
EG Varlamova - Cells, 2024 - mdpi.com
… , such as immunosuppressive cancer therapy based on immune checkpoint inhibitors, with
… better results compared with the widely used multikinase inhibitor sorafenib [9], while the …
… better results compared with the widely used multikinase inhibitor sorafenib [9], while the …
Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and …
TM Al-Noshokaty, NM Mesbah, DM Abo-Elmatty… - Life Sciences, 2022 - Elsevier
… The first-line treatment for advanced hepatocellular carcinoma (HCC) is the multikinase
inhibitor … B (NF-κB) activation, apoptosis inhibition and oxidative stress. This study investigated …
inhibitor … B (NF-κB) activation, apoptosis inhibition and oxidative stress. This study investigated …
A Functional Screening Identifies a New Organic Selenium Compound Targeting Cancer Stem Cells: Role of c‐Myc Transcription Activity Inhibition in Liver Cancer
JN Zhou, B Zhang, HY Wang, DX Wang… - Advanced …, 2022 - Wiley Online Library
… the CSC frequencies and inhibit distant metastasis. To our knowledge, it is the first time to
synthesize a selenium-containing small molecule with CSC inhibition potential, at least …
synthesize a selenium-containing small molecule with CSC inhibition potential, at least …
Selenium sulfide disrupts the PLAGL2/C‐MET/STAT3‐induced resistance against mitochondrial apoptosis in hepatocellular carcinoma
T Yang, J Huo, R Xu, Q Su, W Tang… - Clinical and …, 2021 - Wiley Online Library
… Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related deaths
worldwide. Overexpression of pleomorphic adenoma gene like‐2 (PLAGL2) is associated with …
worldwide. Overexpression of pleomorphic adenoma gene like‐2 (PLAGL2) is associated with …
Selenium-rich royal jelly inhibits hepatocellular carcinoma through PI3K/AKT and VEGF pathways in H22 tumor-bearing mice
X Chi, Z Liu, W Wei, X Hu, Y Wang, H Wang, B Xu - Food & Function, 2021 - pubs.rsc.org
… To summarize, the findings clearly demonstrate that Se-rich RJ could inhibit tumor growth …
will die because of liver cancer in 2030. At present, HCC is treated by medical surgery, …
will die because of liver cancer in 2030. At present, HCC is treated by medical surgery, …
Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo
… the reaction of selenium compounds with thiols in mammary tumor cells induces apoptosis
… of treated animals with doxorubicin) presented a significant inhibition of tumor growth and …
… of treated animals with doxorubicin) presented a significant inhibition of tumor growth and …
Selenium nanoparticles and quercetin suppress thioacetamide‐induced hepatocellular carcinoma in rats: Attenuation of inflammation involvement
AA Mohamed, RA Zaghloul… - … of Biochemical and …, 2022 - Wiley Online Library
… Hepatocellular carcinoma (HCC) is a kind of liver tumor, ranking as the third reason for
death among cancer … that QCT inhibited HCC development by inhibiting proliferation and/or …
death among cancer … that QCT inhibited HCC development by inhibiting proliferation and/or …
The effect of methylselenocysteine and sodium selenite treatment on microRNA expression in liver cancer cell lines
G Lendvai, T Szekerczés, E Kontsek, A Selvam… - Pathology & Oncology …, 2020 - Springer
… of the effects of treatment of tumor cells with selenium on microRNA expression have …
inhibitory and cytotoxic effects of selenium, offering a therapeutic window for cancer treatment…
inhibitory and cytotoxic effects of selenium, offering a therapeutic window for cancer treatment…
The composites of triple-helix glucan nanotubes/selenium nanoparticles target hepatocellular carcinoma to enhance ferroptosis by depleting glutathione and …
L Cai, S Zhou, B Yu, E Zhou, Y Zheng… - Chemical Engineering …, 2022 - Elsevier
… an antioxidant scavenger and ROS inducer to inhibit hepatocellular carcinoma cell proliferation,
clone, … Overall, this study provides an alternative strategy for cancer therapy by inhibiting …
clone, … Overall, this study provides an alternative strategy for cancer therapy by inhibiting …