Antibiofilm activity of host defence peptides: Complexity provides opportunities

REW Hancock, MA Alford, EF Haney - Nature Reviews Microbiology, 2021 - nature.com
… were substituted for their d-enantiomeric counterparts, has … opportunities of using antimicrobial
peptides against multidrug-… the immunomodulatory activities of host defence peptides

Antimicrobial and anti-inflammatory activities of MAF-1-derived antimicrobial peptide Mt6 and its D-enantiomer D-Mt6 against Acinetobacter baumannii by targeting …

D Kong, X Hua, R Zhou, J Cui, T Wang… - Microbiology …, 2022 - Am Soc Microbiol
… Due to their strong antibacterial action, antimicrobial peptides … Moreover, some cationic
peptides exert immunomodulatory … with conventional antibiotics, stability, an anti-biofilm property, …

Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
… are short, amphiphilic, and highly cationic molecules [5,22]. They have strong antimicrobial
… , have biological functions such as immunomodulatory, antimicrobial, anticancer, and wound …

Dynamic killing effectiveness of mouthrinses and a d-enantiomeric peptide on oral multispecies biofilms grown on dental restorative material surfaces

J Hu, J Yu, H Liu, Z Wang, M Haapasalo, EF Haney… - Journal of Dentistry, 2023 - Elsevier
… The antimicrobial peptide DJK-5 is effective against oral … result from immunomodulation
[22]. In recent years, DJK-5, a … As a d-enantiomeric antibiofilm peptide, DJK-5 is characterized …

The potential of human peptide LL-37 as an antimicrobial and anti-biofilm agent

KE Ridyard, J Overhage - Antibiotics, 2021 - mdpi.com
… The human antimicrobial peptide LL-37 has been … and anti-biofilm activities as well as
immunomodulatory functions. … Despite the strong antimicrobial properties, LL-37 has several …

d-Amino acids in antimicrobial peptides: a potential approach to treat and combat antimicrobial resistance

S Kapil, V Sharma - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Antimicrobial peptides are small, positively charged oligopeptides that are as potent as
commercially available antibiotics … demonstrated a number of immunomodulatory functions, such …

Antimicrobial Peptides: Sources, Types, and Antibiofilm Activity

K Bhavini, A Fernandes, V Ravichandran, D Lahiri… - Natural … - taylorfrancis.com
Antimicrobial peptides have a varied range of activity against … Most AMPs have varied
antimicrobial and antibiofilm potency. For … D-enantiomeric peptides that eradicate wild-type and …

Fighting Pseudomonas aeruginosa Infections: Antibacterial and Antibiofilm Activity of D-Q53 CecB, a Synthetic Analog of a Silkworm Natural Cecropin B Variant

I Varponi, S Ferro, L Menilli, A Grapputo… - International Journal of …, 2023 - mdpi.com
… to increase tolerance to some antimicrobials peptides (AMPs) (ie, … L- and D-Q53 CecB
peptides showed similar and strong … Pioneering studies have shown that D-enantiomeric forms of …

Potent intracellular antibacterial activity of a marine peptide-N6NH2 and its D-enantiomer against multidrug-resistant Aeromonas veronii

T Li, Z Wang, H Han, D Teng, R Mao, Y Hao… - Applied Microbiology …, 2021 - Springer
Antimicrobial peptides (AMPs) are currently the most promising new drugs in the fight against
bacteria, including MDR bacteria due to their excellent antimicrobialimmunomodulatory

Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties

ON Silva, MDT Torres, J Cao… - Proceedings of the …, 2020 - National Acad Sciences
peptides with potent immunomodulatory and antimicrobial … search and analysis of the
Antimicrobial Peptides Database (26) … Mast-MO (4 μg mL −1 ) also exhibited increased antibiofilm