… in defense reactions to trematode invasion and resistance to … of somatic diversification has
been shown for FREP2, FREP3… Investigation of a neglected African snail that supports more S. …

… and SmPoMucs act as determinants of compatibility, thus … FREP2 and of FREP3 distinct
to RES snails. One version of … suggestive of a separate diversification is observed including …

… Many factors contribute to the schistosomiasis establishment in … The defense system of snails
is translated into several molecular … FREP3 has a strong relationship with the phenotype of …

… to further our understanding of snail biology. This review … of vector snails and the role
invertebrate immunity plays in defense … advance the discovery of determinants of host …

… in category 4 snails undergoing active resistance responses (52 … of a GPCR role in defense
against schistosome infection. … homolog of FREP3.2 over-expressed in Category 2 snails is …

… These snails also act as vectors for the transmission of schistosomiasis in livestock and …
snails, helps provide a framework to explain the complex patterns of compatibility between snails …

… suite of other immune factors, as being important elements of the snail immune response to
… the known determinants of snail resistance to S. mansoni work in concert to protect the snail …

… resistant and susceptible snails. It also includes the current understanding of the immune
molecular determinants … FREPs are unique in their capacity for somatic diversification, which …

… factors involved in snail immune defense (46, 99). Based on comparative approaches between
susceptible and resistant snail … of pathogens by at least FREP3 and biomphalysin (s) to …

… promotes the expression of defense genes for inflammatory … hosts are the main determinants
for successful infection. An … snails, such as the putative immune receptor FREP3 [108], Cu/…