A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2
… membrane protein, and nucleoproteins are shown in Figure 2. In the case of the spike
glycoprotein (Figure 2A), we identify … regions associated with high immune response rates. Three …
glycoprotein (Figure 2A), we identify … regions associated with high immune response rates. Three …
Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes
… bioinformatics platform, we identify multiple putative epitopes that are potential targets for CD4
+ and CD8 + T cells… structural proteins are the spike protein (S), the membrane protein (M)…
+ and CD8 + T cells… structural proteins are the spike protein (S), the membrane protein (M)…
The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance
ID Ferguson, B Patiño-Escobar, ST Tuomivaara… - Nature …, 2022 - nature.com
… surface antigens and identify CCR10 as a promising target in … Human Protein Atlas 26 , as
well as bioinformatic prediction … ) was by far the most increased surface protein in CfzR cells, …
well as bioinformatic prediction … ) was by far the most increased surface protein in CfzR cells, …
Identification of vaccine targets in pathogens and design of a vaccine using computational approaches
… screening, we filtered TC-CLB proteins using a set of bioinformatics tools. First, we used the
… family such as trans-sialidases, and mucin-associated surface protein were present in the …
… family such as trans-sialidases, and mucin-associated surface protein were present in the …
Gene function and cell surface protein association analysis based on single-cell multiomics data
… cell surface proteins have been the targets of the approved drugs for human diseases [22,28].
Cell surface proteins … most studies and their potential functions have not been investigated. …
Cell surface proteins … most studies and their potential functions have not been investigated. …
Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane
… ) for quantified cell surface proteins in K562 cells by TPP without and with cell surface protein
… enrichment step on thermal stability measurements of cell surface proteins, we compared …
… enrichment step on thermal stability measurements of cell surface proteins, we compared …
Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform
… and therapeutic targets. However, our understanding of … The focus of this paper is directed
at defining surface protein … Proteins selected for downstream bioinformatics analysis …
at defining surface protein … Proteins selected for downstream bioinformatics analysis …
Design of protein-binding proteins from the target structure alone
… most promising binding modes. We demonstrate the broad applicability of this approach
through the de novo design of binding proteins … For each of these surface proteins, we selected …
through the de novo design of binding proteins … For each of these surface proteins, we selected …
A human IgSF cell-surface interactome reveals a complex network of protein-protein interactions
… cell-surface proteins (excluding antibodies and T cell receptors), along with other select proteins
… The IgSF is the largest and most functionally diverse family in the cell-surface proteome. …
… The IgSF is the largest and most functionally diverse family in the cell-surface proteome. …
Bioinformatics analysis of epitope-based vaccine design against the novel SARS-CoV-2
HZ Chen, LL Tang, XL Yu, J Zhou, YF Chang… - Infectious diseases of …, 2020 - Springer
… This study aimed to predict the protective epitopes with bioinformatics methods and resources
… The purpose of this study is to predict B-cell epitopes on spike protein and T-cell epitopes …
… The purpose of this study is to predict B-cell epitopes on spike protein and T-cell epitopes …