… , extrudes DNA loops using an ATP‐dependent mechanism that … , such external supercoils
could imply that condensin‐DNA … Here, using cryo‐EM and biochemical experiments we show …

… electron-imaging 13 studies of condensin I from Xenopus … in an ATP-dependent manner.
Finally, we discuss how our in … for positively supercoiled DNA with those for relaxed DNA in the …

… without melting DNA, as positively supercoiled DNA is more … and condensin (for an in-depth
recent review, see Reference 64). … ATP: the DNA-compacting DNA gyrase is ATP dependent, …

… The aim of this work was to biochemically and biophysically … Ct condensin can compact
DNA in an ATP-dependent manner… stimulated by DNA (Figure 13) and that DNA compaction is …

… condensin can unload from DNA in an ATPdependent … is whether the positive supercoiling
activity of condensin is strong … two main biochemical assays used to probe condensin-DNA …

… DNA passage but nevertheless allows ATP-dependent … -EM structures in conjunction with
biochemical mapping reveal a … safety belt in cohesin (12, 13) presumably allows for a frequent …

… double-stranded DNA segment in an ATP dependent manner [ … similar to a fractal globule,
[ 13, 14 ] such that any segment of … However, in biological systems, specific DNA sequences …

… these states in an ATP-dependent fashion. In addition, we find … findings imply for a mechanistic
model for SMC-mediated DNA… a new piece of DNA to reel it in 13,45 . Our observation that …

… in regulating diverse biological processes. Although … We showed that the condensin
dosage compensation … In this theory, called the “twin domain model,” positive supercoils …

… 13−17) where a DNA loop trapped by the protein progressively elongates via an ATP-mediated
translocation. On the biochemical level, however, condensins … Lysines implicated in DNA …