The mechanism and therapy of aortic aneurysms
… aneurysms to find new targets for diagnosis and treatment. To better understand aortic
aneurysm… Type I lesions extend from the ascending aorta to the abdominal aorta, and the lining of …
aneurysm… Type I lesions extend from the ascending aorta to the abdominal aorta, and the lining of …
Novel pharmacological approaches in abdominal aortic aneurysm
L Puertas-Umbert, R Almendra-Pegueros… - Clinical …, 2023 - portlandpress.com
… Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health …
need for therapy. This disease is featured by a progressive dilation of the abdominal aorta, …
need for therapy. This disease is featured by a progressive dilation of the abdominal aorta, …
Mechanisms of abdominal aortic aneurysm progression: A review
JP Gao, W Guo - Vascular Medicine, 2022 - journals.sagepub.com
… Up to now, there is still controversy on the choice of treatment method of AAA. Even so,
the mechanisms of AAA progression are poorly defined, making targeting new therapies …
the mechanisms of AAA progression are poorly defined, making targeting new therapies …
Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm
B Liu, DJ Granville, J Golledge… - American Journal of …, 2020 - journals.physiology.org
… Research over the past decade has identified novel contributors to aneurysm … abdominal
aortic aneurysm growth and efforts underway to develop effective pharmacological treatments …
aortic aneurysm growth and efforts underway to develop effective pharmacological treatments …
A novel mechanism underlying inflammatory smooth muscle phenotype in abdominal aortic aneurysm
… MMP2 and MMP9 mRNA levels were assessed by RT-PCR at 0, 2, 4, and 6 h following the
treatment (F) and normalized to the mean level before the actinomycin treatment (0 h), which …
treatment (F) and normalized to the mean level before the actinomycin treatment (0 h), which …
Promising novel therapies in the treatment of aortic and visceral aneurysms
TM Stougiannou, KC Christodoulou… - Journal of Clinical …, 2023 - mdpi.com
… Atherosclerosis, although more frequently implicated in descending thoracic and abdominal
aortic aneurysms, might also be an etiologic factor for TAAAs and VAAs [13,14], while …
aortic aneurysms, might also be an etiologic factor for TAAAs and VAAs [13,14], while …
Development of pharmacotherapies for abdominal aortic aneurysms
… The cardiovascular field is still searching for a treatment for abdominal aortic aneurysms (AAA).
This inflammatory disease often goes undiagnosed until a late stage and associated …
This inflammatory disease often goes undiagnosed until a late stage and associated …
Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
… , understanding of novel immune mediated mechanisms regulating AAA development and
factors driving pathogenic immune cell activation will pave the road for novel therapeutics and …
factors driving pathogenic immune cell activation will pave the road for novel therapeutics and …
Pathogenesis and management of abdominal aortic aneurysm
J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
… and therapies to limit AAA growth. Genome-wide association studies have identified novel
drug targets… Mendelian randomization analyses suggest that treatments to reduce low-density …
drug targets… Mendelian randomization analyses suggest that treatments to reduce low-density …
[HTML][HTML] Innovation in pathogenesis and management of aortic aneurysm
M Barkhordarian, HHV Tran, A Menon… - World Journal of …, 2024 - ncbi.nlm.nih.gov
… We also highlighted the novel management methods that … thoracic aortic aneurysm (TAA),
abdominal aortic aneurysms (… to aortic aneurysms has a dynamic landscape of treatment …
abdominal aortic aneurysms (… to aortic aneurysms has a dynamic landscape of treatment …