Wild-Type Isocitrate Dehydrogenase-Dependent Oxidative Decarboxylation and Reductive Carboxylation in Cancer and Their Clinical Significance
Q He, J Chen, Z Xie, Z Chen - Cancers, 2022 - mdpi.com
… dehydrogenases in metabolism, provide a current overview of cancer-… in microvessel density
and tumor growth, suggesting an … IDH3α promotes the upregulation of the expression of …
and tumor growth, suggesting an … IDH3α promotes the upregulation of the expression of …
A Molecular Perspective on HIF-1α and Angiogenic Stimulator Networks and Their Role in Solid Tumors: An Update
… a metabolic shift towards aerobic glycolysis, even under normoxic conditions (Warburg effect)
[31]. This metabolic switch promotes tumor growth and … to aberrant angiogenesis in cancer …
[31]. This metabolic switch promotes tumor growth and … to aberrant angiogenesis in cancer …
Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments.
L Zhang, Y Song, X Dai, W Xu, M Li, Y Zhu - Cancers, 2023 - europepmc.org
… not clear whether the aberrant expression of IDH3α is related to … of IDH3α expression on
tumor growth after cisplatin treatment. … Overall, high expression of IDH3α promoted metabolic …
tumor growth after cisplatin treatment. … Overall, high expression of IDH3α promoted metabolic …
Mutant IDH in gliomas: Role in cancer and treatment options
… , while silencing IDH3α was observed to obstruct tumour growth [161]… The different
consequences of IDH3α aberrant expression … metabolic requirements of each tissue during …
consequences of IDH3α aberrant expression … metabolic requirements of each tissue during …
Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments
L Zhang, Y Song, X Dai, W Xu, M Li, Y Zhu - Cancers, 2023 - mdpi.com
… not clear whether the aberrant expression of IDH3α is related to … of IDH3α expression on
tumor growth after cisplatin treatment. … Overall, high expression of IDH3α promoted metabolic …
tumor growth after cisplatin treatment. … Overall, high expression of IDH3α promoted metabolic …
[PDF][PDF] Oncometabolite 2-hydroxyglutarate regulates anti-tumor immunity
M Cai, J Zhao, Q Ding, J Wei - Heliyon, 2024 - cell.com
… TIME plays a critical role in regulating tumor development and antitumor … Aberrant
IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic …
IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic …
[HTML][HTML] Biological roles and therapeutic applications of IDH2 mutations in human cancer
J Guo, R Zhang, Z Yang, Z Duan, D Yin… - Frontiers in …, 2021 - frontiersin.org
… against lipid oxidation-induced reactive oxygen species (ROS) (18). IDH3α was also considered
… factor-1, which promotes metabolic reprogramming of cancer cells and angiogenesis of …
… factor-1, which promotes metabolic reprogramming of cancer cells and angiogenesis of …
[HTML][HTML] The relative isoform expression levels of isocitrate dehydrogenase in breast cancer: IDH2 is a potential target in MDA-MB-231 cells
S Piao, S Kim, Y Seo, J Lee, S Jeon… - Korean Journal of …, 2023 - ncbi.nlm.nih.gov
… Like other cancers, breast cancer requires metabolic reprogramming to sustain its biosynthetic
and … to assess the aberrant formation of primer dimers. Relative expression levels were …
and … to assess the aberrant formation of primer dimers. Relative expression levels were …
[HTML][HTML] Metabolic plasticity of melanoma cells and their crosstalk with tumor microenvironment
A Avagliano, G Fiume, A Pelagalli, G Sanità… - Frontiers in …, 2020 - frontiersin.org
… with TME, leading to tumor development, therapeutic resistance and … Furthermore, it has
been reported that the aberrant and … IDH3α, a key enzyme in the TCA cycle, regulates metabolic …
been reported that the aberrant and … IDH3α, a key enzyme in the TCA cycle, regulates metabolic …
Isoforms of IDH in breast carcinoma: IDH2 as a potent prognostic factor associated with proliferation in estrogen-receptor positive cases
H Minemura, K Takagi, A Sato, M Yamaguchi… - Breast Cancer, 2021 - Springer
… Aberrant IDH3α expression also reported to promote malignant tumor growths by inducing
… alteration of IDH1-3 expression is possibly link to the metabolic adaptation and IDH2 alone …
… alteration of IDH1-3 expression is possibly link to the metabolic adaptation and IDH2 alone …