… applications of these inhibitors. This review is focused on a survey of cholinesterase
inhibitors with known or expected pharmacological impact and indications of their use. Recent …

… The main class of drugs currently used for the treatment of AD are acetylcholinesterase/cholinesterase
inhibitors (ChE-Is). The first ChE-I licensed for symptomatic treatment of AD was …

… B detection based on acetylcholinesterase inhibition. Anal. Chem., … Biosensors based on
cholinesterase inhibition for … Potent carbonic anhydrase and acetylcholinesterase inhibitors. …

… comorbidities lead to altered pharmacological responses and increased ADRs. Furthermore,
geriatric people are more likely to be sensitive to pharmacological toxicity. The most …

… To identify AChE inhibitors rapidly and efficiently, we have screened the Toxicology in the …
cell-based AChE inhibition assay and enzyme-based AChE inhibition assays (with or without …

… reason, cholinesterase inhibitors can be divided into two general classes: (i) ‘single target’
ligands that specifically inhibit AChE/BuChE; (ii) ‘multi-target’ cholinesterase inhibitors that …

… Moreover, several acetylcholinesterase inhibitors (AChEIs) that interact with the PAS, such
as donepezil or physostigmine, unlike inhibitors that bind only the CAS, are able to inhibit …

… Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to
nerve agents can cause rapid death. In this review, we summarize the history of nerve agent …

… inhibitors present long residence times on target. This results in prolonged pharmacological
or toxicological … -binding inhibitors of acetylcholinesterase are promising drugs for treatment …

… the major cholinesterase in the circulation, whereas AChE is the leading cholinesterase in
… ’, the sum capacity for acetylcholine (ACh) hydrolysis in one's body, and inhibitors of these …