Actin-based protrusions at a glance
S Belian, O Korenkova, C Zurzolo - Journal of Cell Science, 2023 - journals.biologists.com
S Belian, O Korenkova, C Zurzolo
Journal of Cell Science, 2023•journals.biologists.comActin-based protrusions are at the base of many fundamental cellular processes, such as
cell adhesion, migration and intercellular communication. In recent decades, the discovery
of new types of actin-based protrusions with unique functions has enriched our
comprehension of cellular processes. However, as the repertoire of protrusions continues to
expand, the rationale behind the classification of newly identified and previously known
structures becomes unclear. Although current nomenclature allows good categorization of …
cell adhesion, migration and intercellular communication. In recent decades, the discovery
of new types of actin-based protrusions with unique functions has enriched our
comprehension of cellular processes. However, as the repertoire of protrusions continues to
expand, the rationale behind the classification of newly identified and previously known
structures becomes unclear. Although current nomenclature allows good categorization of …
Abstract
Actin-based protrusions are at the base of many fundamental cellular processes, such as cell adhesion, migration and intercellular communication. In recent decades, the discovery of new types of actin-based protrusions with unique functions has enriched our comprehension of cellular processes. However, as the repertoire of protrusions continues to expand, the rationale behind the classification of newly identified and previously known structures becomes unclear. Although current nomenclature allows good categorization of protrusions based on their functions, it struggles to distinguish them when it comes to structure, composition or formation mechanisms. In this Cell Science at a Glance article, we discuss the different types of actin-based protrusions, focusing on filopodia, cytonemes and tunneling nanotubes, to help better distinguish and categorize them based on their structural and functional differences and similarities.
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