Autophagy alleviates amiodarone-induced hepatotoxicity

F Wandrer, Ž Frangež, S Liebig, K John, F Vondran… - Archives of …, 2020 - Springer
… During apoptosis, caspases are activated and cleave various substrates including keratin-…
Amiodarone-induced apoptosis, ER-stress and autophagy in primary human hepatocytes. a …

Autophagy, an important therapeutic target for pulmonary fibrosis diseases

H Zhao, Y Wang, T Qiu, W Liu, P Yao - Clinica chimica acta, 2020 - Elsevier
activated in amiodarone-induced pulmonary fibrosis. Additionally, the extensive macroautophagy
causes the apoptosis of type II alveolar epithelial cells (… -autophagy and rescues CFTR …

Regulation of autophagy in animal models of pulmonary fibrosis

S Ahuja - 2020 - jlupub.ub.uni-giessen.de
… exogenous LC3B mediated autophagy rescue in A549 cells. … the alveolar epithelium, which
results in a continuous activation of … epithelial cell apoptosis which might result from several …

Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1

SY Wu, JW Chen, HY Liu, YC Wang, YS Chu… - Journal of biomedical …, 2022 - Springer
… accompanied by amiodarone-induced autophagy led to … activates both Rab37 and autophagy,
and Rab37/autophagy, in … in the death of lung epithelial cells and pulmonary toxicity [52]. …

Amiodarone promotes heat-induced apoptosis, inflammation and oxidative stress in mouse HL1 atrial myocytes

H Zhao, Z Tan, L He, S Zhu, R Yan, H Kou… - Nan Fang yi ke da xue …, 2021 - europepmc.org
… Heat exposure of HL1 atrial myocytes was conducted using a water bath, and the effect
of amiodarone on cell viability was assessed with MTS method; cell apoptosis was detected …

BMSCs mediates endothelial cell autophagy by upregulating miR‐155‐5p to alleviate ventilator‐induced lung injury

X Lin, T Yu, J Luo, L Chen, Y Liu, J Xu… - … of Biochemical and …, 2022 - Wiley Online Library
activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and
pulmonary … [ 37 ] Similar to the former study, our results illustrated that autophagy might act as …

Caveolin-1 scaffolding domain peptide abrogates autophagy dysregulation in pulmonary fibrosis

S Venkatesan, L Fan, H Tang, NV Konduru… - Scientific Reports, 2022 - nature.com
apoptosis and activation of myofibroblasts and fibrotic lung … regulate extrinsic apoptosis via
Fas in lung epithelial cells 27 . … is that we did not perform long-term rescue/recovery study, it is …

Lysosomal dysfunction in carbon black-induced lung disorders

M Gao, X Ge, Y Li, G Zheng, J Cai, J Yao… - Science of The Total …, 2023 - Elsevier
… In alveolar epithelial cells, CB exposure resulted in decreased cell viability, induction of cell
death, … Cell line of human lung adenocarcinoma epithelial cells A549 were purchased from …

Lungs

P Mahavadi, M Korfei, A Guenther - Autophagy in Health and Disease, 2022 - Elsevier
Autophagy in this context is believed to be a protective mechanism to rescue dying lung
epithelial cells. … activation of the autophagy protein LC3B, which in turn regulates Fas-mediated …

Non-apoptotic programmed cell deaths in diabetic pulmonary dysfunction: the new side of advanced glycation end products

Y Dai, S Zhou, L Qiao, Z Peng, J Zhao, D Xu… - Frontiers in …, 2023 - frontiersin.org
… roles of non-apoptotic PCDs including autophagic cell death, … is enough to rescue the cells
from inevitable decompensation … autophagy and activation of autophagic proteins in epithelial