[HTML][HTML] Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications
A Rai, M Narisawa, P Li, L Piao, Y Li, G Yang… - … of hypertension, 2020 - journals.lww.com
… [51] studied activation of human T cells in humanized mice and hypertensive humans.
They found that human T cells became activated and invaded critical end-organ tissues in …
They found that human T cells became activated and invaded critical end-organ tissues in …
[HTML][HTML] Immune mechanisms in arterial hypertension. Recent advances
UO Wenzel, H Ehmke, M Bode - Cell and Tissue Research, 2021 - Springer
… -17A producing CD4 + T cells and both CD4 + and CD8 + T cells that produce IFN-γ …
hypertensive compared with normotensive humanized mice. Thus, human T cells become activated …
hypertensive compared with normotensive humanized mice. Thus, human T cells become activated …
Angiotensin II-induced memory γδ T cells sensitize mice to a mild hypertensive stimulus
K Comeau, B Shokoples, A Caillon… - … of Hypertension, 2023 - academic.oup.com
… T cells develop after a hypertensive challenge and sensitize mice to develop hypertension in
… demonstrated in humanized mice that BP elevation, but not AngII, induced the development …
… demonstrated in humanized mice that BP elevation, but not AngII, induced the development …
Immune profiling reveals decreases in circulating regulatory and exhausted T cells in human hypertension
… The majority of the patients with hypertension in this study were on antihypertensive
medications. Although a variety of medications were used, thus reducing the chance that one …
medications. Although a variety of medications were used, thus reducing the chance that one …
Immune system and microvascular remodeling in humans
… unconventional T lymphocytes like γδ T cells contribute to hypertension and … of
hypertension-mediated organ damage in humans. Several studies have also suggested that …
hypertension-mediated organ damage in humans. Several studies have also suggested that …
Immune and inflammatory mechanisms in hypertension
TJ Guzik, R Nosalski, P Maffia… - Nature Reviews …, 2024 - nature.com
… T lymphocytes (CD45RO + ), features of T cell activation 30 … These two pivotal studies
demonstrated that this cholinergic … for T cell activation and egression in response to hypertensive …
demonstrated that this cholinergic … for T cell activation and egression in response to hypertensive …
Interleukin 17A: key player in the pathogenesis of hypertension and a potential therapeutic target
GK Davis, DJ Fehrenbach, MS Madhur - Current hypertension reports, 2021 - Springer
… models of hypertension and in hypertensive humans [19••, 20]… in hypertensive mouse
kidneys and aortas, the major T cell … cells and γδ T cells with lesser contribution from other T cell …
kidneys and aortas, the major T cell … cells and γδ T cells with lesser contribution from other T cell …
Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension
CM Ferrario, JL VonCannon, J Zhang, JP Figueroa… - Peptides, 2022 - Elsevier
… hypertensive rats [TGR(hAGT)L1623] expressing the human sequence … hypertension in
TGR(hAGT)L1623 hypertensive rats is accompanied by increased circulating levels of the human …
TGR(hAGT)L1623 hypertensive rats is accompanied by increased circulating levels of the human …
Role of interleukin-23/interleukin-17 axis in T-cell-mediated actions in hypertension
… play an initiating role in the development of hypertension in mouse hypertensive … T cells
play a role in hypertension has been challenged by some reports. Namely, Rag1-deficient mice …
play a role in hypertension has been challenged by some reports. Namely, Rag1-deficient mice …
T-cell senescence accelerates angiotensin II-induced target organ damage
XX Pan, F Wu, XH Chen, DR Chen… - … Research, 2021 - academic.oup.com
… To detect the distribution of T cells in recipient mice, we examined the CD3 + T cells in …
Activation of human T cells in hypertension: studies of humanized mice and hypertensive humans …
Activation of human T cells in hypertension: studies of humanized mice and hypertensive humans …