Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating the SIRT2-p65 pathway

M Liu, Z Shi, Y Yin, Y Wang, N Mu, C Li, H Ma… - Frontiers of …, 2021 - Springer
… the whole body systems via their proinflammatory effects [1]. … κB) activation in PM2.5-induced
proinflammatory responses [9… analysis of goblet cells of the bronchial mucosa, and Masson’…

Particulate matter induces tissue oxinflammation: from mechanism to damage

G Valacchi, N Magnani, B Woodby… - Antioxidants & Redox …, 2020 - liebertpub.com
Activation of inflammatory cells capable of generating … the cell also starts to experiment a
proinflammatory response … tissues (ie, airway and skin) are likely to be activated in the gut, …

Inflammatory effects of particulate matter air pollution

RD Arias-Pérez, NA Taborda, DM Gómez… - … Science and Pollution …, 2020 - Springer
cells produce pro-inflammatory mediators after phagocytosing PM that contributes to the
lung immune response, … PM10 activates the NLRP3 inflammasome in airway epithelial cells, …

Particulate matters induce acute exacerbation of allergic airway inflammation via the TLR2/NF-κB/NLRP3 signaling pathway

MY Dai, FF Chen, Y Wang, MZ Wang, YX Lv, RY Liu - Toxicology letters, 2020 - Elsevier
airway inflammation and NLRP3 inflammasome activation in vivo, … of inflammatory cells,
mucus secretion around the airway and … of pro-inflammatory factors, epithelial cells damage, and …

Urban particulate matters may affect endoplasmic reticulum stress and tight junction disruption in nasal epithelial cells

SK Park, SH Yeon, MR Choi, SH Choi… - American Journal of …, 2021 - journals.sagepub.com
… nasal mucosa is the first line of defense in the respiratory tract … , mutagenicity, and activation
of pro-inflammatory factors. And … UPMs induce the activation of ER stress responses and …

Particulate matter 2.5 causes deficiency in barrier integrity in human nasal epithelial cells

M Xian, S Ma, K Wang, H Lou, Y Wang… - Allergy, asthma & …, 2020 - synapse.koreamed.org
… to higher activation of subepithelial cells, such as immune cells.… to chronic mucosal
inflammatory disease by impairing airway … it induces production of proinflammatory cytokines, …

Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway

L Hu, C Xu, X Tang, S Yu… - International …, 2023 - spandidos-publications.com
… of PM2.5-induced pro-inflammatory factor production, namely … .5-induced airway inflammation
and mucus hypersecretion, … , and activate the inflammatory response to external stimuli (51…

Aesculetin inhibits airway thickening and mucus overproduction induced by urban particulate matter through blocking inflammation and oxidative stress involving …

SY Oh, YH Kim, MK Kang, EJ Lee, DY Kim, H Oh… - Antioxidants, 2021 - mdpi.com
… Fine PM initiates type 2 cytokines-evoked pro-inflammatory immune responses in … In the
present study EGFR activation was involved in the mucus production from airway epithelial cells

[HTML][HTML] Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke …

ES Son, JW Park, YJ Kim, SH Jeong, JH Hong, SH Kim… - Toxicology in Vitro, 2020 - Elsevier
pro-inflammatory effects of combined exposure to PM and CSE on bronchial epithelial cells,
activation of epithelial cells and macrophages and the subsequent release of mediators in …

Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells

DC Lee, H Choi, JM Oh, J Lee, J Lee, HY Lee, JY Kang - Toxicology Letters, 2020 - Elsevier
… irritation of the airway mucosa, which induces the inflammatory responses, causes cellular
injury, … PM-mediated inflammatory responses include the release of proinflammatory cytokines …