The aryl hydrocarbon receptor suppresses chronic smoke-induced pulmonary inflammation
N Guerrina, H Traboulsi, DH Eidelman… - Frontiers in …, 2021 - frontiersin.org
… aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor expressed in the
lungs that is activated … can reduce inflammation caused by chronic cigarette smoke exposure, …
lungs that is activated … can reduce inflammation caused by chronic cigarette smoke exposure, …
[HTML][HTML] Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic …
N Guerrina, H Traboulsi, AR de Souza… - … : official publication of …, 2021 - ncbi.nlm.nih.gov
… Cigarette smoke is a complex mixture that activates … component of the immune response
to cigarette smoke. Not only do we report that lung and systemic AHR expression is reduced in …
to cigarette smoke. Not only do we report that lung and systemic AHR expression is reduced in …
Aryl hydrocarbon receptor is involved in the proinflammatory cytokine response to cadmium
J Kulas, D Tucovic, M Zeljkovic, D Popovic… - Biomedical and …, 2021 - Elsevier
… The aryl hydrocarbon receptor (AhR) is a ligandactivated … , Germany). A minimum of 10,000
events was acquired each time. … that decreased IL-1β production was not due to decreased …
events was acquired each time. … that decreased IL-1β production was not due to decreased …
The complex biology of aryl hydrocarbon receptor activation in cancer and beyond
… In addition to its many other functions, the ligand-activated transcription factor aryl hydrocarbon
receptor (AHR) is an important regulator of tumor progression. By modulating both tumor …
receptor (AHR) is an important regulator of tumor progression. By modulating both tumor …
6-Formylindolo[3,2-b]carbazole, a Potent Ligand for the Aryl Hydrocarbon Receptor Produced Both Endogenously and by Microorganisms, can Either Promote or …
A Rannug - Frontiers in Toxicology, 2022 - frontiersin.org
… The effects of transient activation of AHR by FICZ differ … activate AHR, IL4I1 may have a role
to play in anti-inflammatory responses, as well as in a tumor escape mechanism that reduces …
to play in anti-inflammatory responses, as well as in a tumor escape mechanism that reduces …
The aryl hydrocarbon receptor in the pathogenesis of environmentally-induced squamous cell carcinomas of the skin
C Vogeley, KM Rolfes, J Krutmann… - Frontiers in …, 2022 - frontiersin.org
… tobacco smoke (32–34). The genotoxic potential of PAHs is primarily unleashed by their
activation … growth factor receptor-2, which acts mitogenic and thereby may reduce apoptotic cell …
activation … growth factor receptor-2, which acts mitogenic and thereby may reduce apoptotic cell …
Aryl hydrocarbon receptor (AhR) activation contributes to high‐fat diet‐induced vascular dysfunction
JF da Silva, JA Bolsoni, RM da Costa… - British journal of …, 2022 - Wiley Online Library
… Aryl hydrocarbon receptor (AhR) antagonism decreases LPC effects on NO and cytokine
levels in endothelial cells. (a) Cyp1a1, (b) IL-1β and (c) eNOS mRNA expression in endothelial …
levels in endothelial cells. (a) Cyp1a1, (b) IL-1β and (c) eNOS mRNA expression in endothelial …
Aryl hydrocarbon receptor signaling synergizes with TLR/NF-κB-signaling for induction of IL-22 through canonical and non-canonical AhR pathways
Y Ishihara, SY Kado, KJ Bein, Y He… - Frontiers in …, 2022 - frontiersin.org
… after activation of the aryl hydrocarbon receptor (AhR) when cells are activated through the
Toll-like receptor (… The mutation of the NF-κB element caused a reduced LPS-induced IL-22 …
Toll-like receptor (… The mutation of the NF-κB element caused a reduced LPS-induced IL-22 …
Ozone-induced aryl hydrocarbon receptor activation controls lung inflammation via interleukin-22 modulation
C Michaudel, F Bataille, I Maillet, L Fauconnier… - Frontiers in …, 2020 - frontiersin.org
… , Germany), lung was collected and sampled for analyses. … , a lower expression of IL-22 in
T cells and a slight decrease of … the COPD model induced by cigarette smoke (55, 56) and …
T cells and a slight decrease of … the COPD model induced by cigarette smoke (55, 56) and …
Targeting the aryl hydrocarbon receptor in stem cells to improve the use of food as medicine
… -induced activation of the aryl hydrocarbon receptor (AhR) … Reduced levels of AhR ligands,
such as indole-3-acetic acid and indole-3-sulfate, are observed in the feces and blood of germ…
such as indole-3-acetic acid and indole-3-sulfate, are observed in the feces and blood of germ…