… T-cell chimerism at 3 months followed by donor lymphocyte infusion is independently associated with favorable outcomes in alemtuzumab-based reduced-intensity …
G McIlroy, E Nikolousis, N Abou-Zeid… - Leukemia & …, 2020 - Taylor & Francis
… for 100 patients, and CD3+ T-cell compartment results were … a strong association between
acute GVHD occurrence and … 3-month FC in whole marrow was predictive of better RFS and …
acute GVHD occurrence and … 3-month FC in whole marrow was predictive of better RFS and …
Risk factors for graft-versus-host-disease after donor lymphocyte infusion following T-cell depleted allogeneic stem cell transplantation
EAS Koster, PA von dem Borne, P Van Balen… - Frontiers in …, 2024 - frontiersin.org
… the clearest indicator for induction of alloreactivity after DLI, … signs of GvHD based on the
anticipated risk of severe GvHD. … in other clinical settings, since BM chimerism, ALC and viral …
anticipated risk of severe GvHD. … in other clinical settings, since BM chimerism, ALC and viral …
Quantitative chimerism in CD3-negative mononuclear cells predicts prognosis in acute myeloid leukemia patients after hematopoietic stem cell transplantation
A Bouvier, J Riou, S Thépot, A Sutra Del Galy… - Leukemia, 2020 - nature.com
… (MAC), reduced toxicity myeloablative (RTC), reduced intensity … on two successive points
is a strong predictive factor of … occurring on donor cells cannot be detected by chimerism, as …
is a strong predictive factor of … occurring on donor cells cannot be detected by chimerism, as …
[HTML][HTML] Early mixed lymphoid donor/host chimerism is associated with improved transplant outcome in patients with primary or secondary myelofibrosis
HJ Deeg, RB Salit, T Monahan, G Schoch… - Biology of Blood and …, 2020 - Elsevier
… Except for acute GVHD, this analysis was based on the most … A time-dependent indicator
variable was used to define … , might suggest the possibility of titrating the amount of donor T cells …
variable was used to define … , might suggest the possibility of titrating the amount of donor T cells …
The predictive value of T-cell chimerism for disease relapse after allogeneic hematopoietic stem cell transplantation
Z Li, J Wang, L Deng, X Liu, F Kong, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
… to verify the predictive value of donor chimerism. In the present … between T-cell chimerism,
PB chimerism, and BM chimerism … Quantitative chimerism in CD3-negative mononuclear cells …
PB chimerism, and BM chimerism … Quantitative chimerism in CD3-negative mononuclear cells …
Peripheral Blood CD34 Donor Chimerism has Greater Clinical Utility Than CD3 for Detecting Relapse after Allogeneic Stem Cell Transplantation for Acute Myeloid …
TP Das, D North, SA Fleming, JLC Tan, A Ivey… - … and Cellular Therapy, 2023 - Elsevier
… risk of triggering severe GVHD after DLI [19]. Chimerism was monitored 4 weeks after AZA or
… To determine whether CD3 + DC added any value to CD34 + DC for predicting relapse, we …
… To determine whether CD3 + DC added any value to CD34 + DC for predicting relapse, we …
[HTML][HTML] … Graft-versus-Host Disease Prophylaxis, and Lower CD3+ T Cell Doses Equalize Rates of Acute and Chronic Graft-versus-Host Disease in Pediatric Patients …
SH Lum, B James, G Ottaviano, AM Ewins… - … and Cellular Therapy, 2024 - Elsevier
… predictors of grade II-IV aGVHD. When considering … a potential strategy to reduce the
risk of severe GVHD in pediatric … impact on graft failure and donor chimerism. There was no …
risk of severe GVHD in pediatric … impact on graft failure and donor chimerism. There was no …
Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation
… acute GVHD was 33% (19 patients) and III to IV acute GVHD … in our study is not informative
in predicting relapse. It is likely … a combined donor chimerism in PBMC or T cells of less than …
in predicting relapse. It is likely … a combined donor chimerism in PBMC or T cells of less than …
Cellular and molecular profiling of T-cell subsets at the onset of human acute GVHD
E Latis, D Michonneau, C Leloup, H Varet… - Blood …, 2020 - ashpublications.org
… of the T-cell compartment, with decreased CD3 + T lymphocytes, compared with their …
donors. Within the CD3 + T-cell population, significantly decreased frequencies of CD4 + …
donors. Within the CD3 + T-cell population, significantly decreased frequencies of CD4 + …
[HTML][HTML] Prognostic Factors for Postrelapse Survival after ex Vivo CD34+-Selected (T Cell-Depleted) Allogeneic Hematopoietic Cell Transplantation in Multiple …
A Gomez-Arteaga, GL Shah, RE Baser… - Biology of Blood and …, 2020 - Elsevier
… differential patterns and predictors of postrelapse survival for … 3 to 4 months later by a dose
of 5 × 10 5 CD3 + cells/kg, and … The median time to onset of acute GVHD was 49 days post-…
of 5 × 10 5 CD3 + cells/kg, and … The median time to onset of acute GVHD was 49 days post-…