… Studies using cDNA microarray in APP-Tg2576 transgenic … in an aged 3xTg-AD restored
cognitive and synaptic deficits … NF-κB, calmodulin kinase, and calcineurin which are involved in …

… –19 months) in transgenic mice (APP mutated gene) has the … can significantly inhibit calcineurin
its use is associated with … mice with double Swedish APP mutation (APPsw/Tg2576). The …

… that are ideal for studying structural brain aging trajectories from serial neuroimaging. Here
we examined the effects of chronic treatment with the calcineurin inhibitor (CNI) tacrolimus or …

… Interestingly, the neuronal overexpression of ADAM10 in transgenic mice reduces BACE1
processing of APP and amyloid deposition, demonstrating how the two secretases compete …

… much higher risk of developing more severe types, which are … system, NMDA receptors, and
inhibitory signaling create an … iTAT mice, but also restored cognitive function. LEV provides …

… Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP
transgenic mice. Neurobiol Learn Mem 2007;88:217-24. …

… Aβ deposition in APP/PS1 double-transgenic mice. Moreover… mice, but were considerably
restored by Rg1 and metformin … was significantly activated in Tg2576 mouse brains, and Ca 2…

… restored dendritic spine densities, plasticity-related proteins and fear learning in the Tg2576
… α-synu or A53T mutant α-syn transgenic mice or control transgenic mice exposed to MPP + . …

… Intriguingly, in an AD transgenic mouse model (APP/PS1), DISC1 hippocampal overexpression
induced mitophagy, resulting in the restoration of mitochondrial metabolism, impairment …

… inhibitors and associated alteration in PTMs were discussed. Lastly, we explored the putative
mechanism of PTMs to restore … In p25 transgenic mice having elevated levels of CDK5 …