… mechanistic basis for Hebbian plasticity and associative learning. … of synaptic function via
activation of calcineurin [39]. … treatment with an α7nAChR agonist restores cognition in AD mice …

… of each APP metabolites that are overexpressed in transgenic … Enhancing inhibitory GABA
current by restoring the level of … to reduce network hypersynchrony, memory deficits, and …

… transgenic mice (Tg2576) over-expressing the human APP … The gene for regulator of
calcineurin 1 (Rcan1) is present on … -APP and its products restored normal activity of Rab5 in vivo. …

… This further activates phosphatase calcineurin to … impaired the memory extinction in the
transgenic Trpc1lox/À … dysfunction produced by Aβ in the tg2576 mice model. In addition, the …

… bearing single or several transgenes that were expressed in … the calcium-dependent
phosphatase calcineurin (CaN), … 3-month-old Tg2576 mice further indicates that abnormally …

… much higher risk of developing more severe types, which are … system, NMDA receptors, and
inhibitory signaling create an … iTAT mice, but also restored cognitive function. LEV provides …

… Synaptic loss was present in APP transgenic models of AD in … Preliminary evidence indicated
that calcineurin, a PP2B serine… vascular and neuronal functions in Tg2576 mice (Table 3). …

… transgenic mice (Tg2576) treated with aluminum in food [26]. The AD-like pathogenesis with
the administration of this metal in the diet of Tg2576 was more severe… , to initiate calcineurin-…

… before sacrificing the mice restored tau phosphorylation. This … Studies on a transgenic
mouse model with Ibuprofen … -1 selective inhibitor SC-560, improved learning and memory and …

… It was shown that IGF-2 treatment restores some cognitive … ruled out, because the furin
inhibitor used in this study was likely … in a study that used APP transgenic mice Tg2576, a genetic …