Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit/stress surfeit disorder
GF Koob, L Vendruscolo - 2023 - Springer
… behavioral impairments that afflict individuals with addiction. Clinically, the occasional but
… substance use disorders (drug addiction), is a reward deficit/stress surfeit disorder, and the …
… substance use disorders (drug addiction), is a reward deficit/stress surfeit disorder, and the …
Stress and addictive disorders
… numerous stress events and examines how stress alters addictive behaviors. Moreover,
novel interventions were developed to alleviate stress-induced PTSD symptoms and addictive …
novel interventions were developed to alleviate stress-induced PTSD symptoms and addictive …
Should reward deficiency syndrome (RDS) be considered an umbrella disorder for mental illness and associated genetic and epigenetic induced dysregulation of …
K Blum, CA Dennen, I Elman, A Bowirrat… - Journal of Personalized …, 2022 - mdpi.com
… to recover from reward deficiency syndrome (RDS) for patients addicted to psychoactive …
in some cases, there is a surfeit rather than a deficit of dopaminergic activity, especially in …
in some cases, there is a surfeit rather than a deficit of dopaminergic activity, especially in …
Neurological correlates of brain reward circuitry linked to opioid use disorder (OUD): Do homo sapiens acquire or have a reward deficiency syndrome?
… “addiction” definition from the American Society of Addiction … addiction is indeed, a brain
disorder is changing the face of … comparison of dopamine surfeit to dopamine deficit theories. …
disorder is changing the face of … comparison of dopamine surfeit to dopamine deficit theories. …
[PDF][PDF] Reward Deficiency Syndrome phase two addiction treatment, targets the unique needs of the individual's brain: Project Reconceptualizing Addiction: The Elle …
ED Gilley - J of Addict Dis & Ment Heal, 2022 - researchgate.net
… was given a Reward Deficiency Syndrome Symptom Checklist, in which she was asked
about her dopamine deficiency symptom experience. The Reward Deficiency Syndrome …
about her dopamine deficiency symptom experience. The Reward Deficiency Syndrome …
[HTML][HTML] Exploration of epigenetic state hyperdopaminergia (Surfeit) and genetic trait hypodopaminergia (Deficit) during adolescent brain development
K Blum, A Bowirrat, MCG Lewis… - Current …, 2021 - ncbi.nlm.nih.gov
… Research into the neurogenetic basis of addiction identified and characterized by Reward
Deficiency Syndrome (RDS) includes all drug and non-drug addictive, obsessive and …
Deficiency Syndrome (RDS) includes all drug and non-drug addictive, obsessive and …
Neurobiology of addiction
… The negative emotional state of withdrawal involves reward deficits and sensitization of
stress systems (stress surfeit) and may engage the activation of the extended amygdala. The …
stress systems (stress surfeit) and may engage the activation of the extended amygdala. The …
The Future is Now for Precision Genomic Addiction Medicine as a Frontline Modality for Inducing “Dopamine Homeostasis” in Reward Deficiency Syndrome (RDS)
ED Gilley, A Bowirrat, A Gupta… - Current …, 2024 - ingentaconnect.com
… of addiction medicine, ideal treatment planning begins with genetic screening to determine
neurogenetic antecedents of the Reward Deficiency … Our laboratory has argued that surfeit …
neurogenetic antecedents of the Reward Deficiency … Our laboratory has argued that surfeit …
[PDF][PDF] THE REWARD DEFICIENCY SYNDROME (RDS) PARADIGM–RDS IS THE PHENOTYPE: ADDICTION AND MENTAL DISORDER ARE ENDOTYPES: ELLE …
ED Gilley - European Journal of Biomedical, 2022 - researchgate.net
… Reward Deficiency Syndrome predisposed family, noting from interview that several generations
have suffered from alcoholism, drug addiction, behavioral addictions … be deficit or surfeit…
have suffered from alcoholism, drug addiction, behavioral addictions … be deficit or surfeit…
Alcohol Use Disorder: Stress, Negative Reinforcement, and Negative Urgency
… ), extended amygdala (reward deficit/stress surfeit), and prefrontal cortex (executive
dysfunction). Here, we discuss key neuroadaptations in stress systems in alcohol addiction. These …
dysfunction). Here, we discuss key neuroadaptations in stress systems in alcohol addiction. These …