[HTML][HTML] Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity
G Desoye, E Herrera - Progress in lipid research, 2021 - Elsevier
During development, the human fetus accrues the highest proportion of fat of all mammals.
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand,
filling with triacylglycerols during pregnancy. The resultant mature lipid-filled adipocytes
emerge from a developmental programme of embryonic stem cells, which is regulated
differently than adult adipogenesis. Fetal triacylglycerol synthesis uses glycerol and fatty
acids derived predominantly from glycolysis and lipogenesis in liver and adipocytes. The …
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand,
filling with triacylglycerols during pregnancy. The resultant mature lipid-filled adipocytes
emerge from a developmental programme of embryonic stem cells, which is regulated
differently than adult adipogenesis. Fetal triacylglycerol synthesis uses glycerol and fatty
acids derived predominantly from glycolysis and lipogenesis in liver and adipocytes. The …
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