[HTML][HTML] Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs

T Zhu, L Wang, L Wang, Q Wan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
… some traditional Chinese medicine (TCM) and natural drugs provide a protective effect against
… the current progress in neuroprotection and neurorestoration in ischemic brain injury and …

[HTML][HTML] Recent advances in nanomedicines for the treatment of ischemic stroke

C Li, T Sun, C Jiang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
… to the lesions, and illustrate the latest progress of nanomedicine in treating ischemic stroke,
… The cascade would eventually lead to irreversible brain damage 13 . Many strategies have …

[HTML][HTML] Recent advances in the development of nanomedicines for the treatment of ischemic stroke

X Tian, T Fan, W Zhao, G Abbas, B Han, K Zhang, N Li… - Bioactive materials, 2021 - Elsevier
… can be prolonged and can accumulate in ischemic brain area [52] … the brain injury area,
and significantly decrease infarct volume and neurological deficit following middle cerebral

Nose to brain drug delivery-a promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion

Y Long, Q Yang, Y Xiang, Y Zhang, J Wan, S Liu… - Pharmacological …, 2020 - Elsevier
… the degree of brain injury, which is called the cerebral ischemia reperfusion injury (CIRI). …
the symptoms temporarily, but cannot inhibit or reverse the progress of I/R. Additionally, the …

Targeting Nrf2‐Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals

AG Wu, YY Yong, YR Pan, L Zhang… - Oxidative Medicine …, 2022 - Wiley Online Library
… In this review, we focused on the research advance of the role of oxidative stress in TBI. At
neutral pH, the iron in plasma is bound to the transferrin protein in the form of Fe 3+ , which …

Brain immune interactions—novel emerging options to treat acute ischemic brain injury

S Muhammad, SR Chaudhry, UD Kahlert, M Niemelä… - Cells, 2021 - mdpi.com
… Despite intensive advancements in medical sciences, the clinical options to treat ischemic
stroke are limited to thrombectomy and thrombolysis using tissue plasminogen activator within …

Targeting myeloperoxidase (MPO) mediated oxidative stress and inflammation for reducing brain ischemia injury: Potential application of natural compounds

S Chen, H Chen, Q Du, J Shen - Frontiers in physiology, 2020 - frontiersin.org
ischemic brain injury, which merits further translational study. … In summary, recent progress
indicates that the study on the … Traditional herbal medicine is an important source for drug

Neuroprotective phytochemicals in experimental ischemic stroke: mechanisms and potential clinical applications

H Xu, E Wang, F Chen, J Xiao… - Oxidative Medicine and …, 2021 - Wiley Online Library
… Neuroprotective agents could reduce ischemic brain injuries … carotid artery (ICA) and
advanced to the origin of MCA to block … To conclude, scutellarin is a key Chinese herbal medicine

Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology

H Chen, Y He, S Chen, S Qi, J Shen - Pharmacological Research, 2020 - Elsevier
… stress and inflammatory responses in ischemic brain injury. The interactions between … amplify
brain damage during cerebral ischemic injury. Furthermore, we review the current progress

Classical active ingredients and extracts of Chinese herbal medicines: pharmacokinetics, pharmacodynamics, and molecular mechanisms for ischemic stroke

T Zhu, L Wang, Y Feng, G Sun… - Oxidative medicine and …, 2021 - Wiley Online Library
… medicinal history in treating cardiovascular disease in Asia [… With the development of
advanced technology, more than 80 … [89, 90]; and antiapoptotic [87] roles in ischemic brain injury. …