… chemists who are working on CA-based drug development field. A detailed critical analysis
of the pharmacological advancement of the newly emerged CAI classes also appears as a …

… advances in the structural annotation of human carbonic anhydrases and the impact on future
drug … . reviewed the structure-activity relationship of human carbonic anhydrase-II inhibitors…

… classical applications of the human (h) CA inhibitors (CAIs), clinically used drugs as diuretics,
antiglaucoma and antiepileptic agents [4,10,24], as well as new developments which led to …

… It should be noted that there is no analysis at all of … drugs or drug design, they questioned
the drug candidate, SLC-0111, which is in Phase Ib/II clinical trials for the treatment of advanced…

… saw many other interesting developments, with some CAIs … All these developments were
only possible due to the fact … X-ray crystal structures of 11 of the 15 human CA isoforms are …

… In the following sections, results obtained from this analysis will … for the future development
of targeted cancer treatments. … CA isoform-selective drugs open novel broad scenarios of …

… are a potential target for therapeutic drugs in the treatment of … about local structural changes
in the structures around the … the analysis of changes of secondary structure difficult for …

… , innovative drug delivery systems, and advanced drug discovery … from clinical trial data
to inform future research. Finally, the … A detailed analysis of their transcriptional organization …

… This study used computer-assisted drug design approach and encourages the harnessing
of natural products as potential CAII inhibitors in the future. Natural compounds identified in …

… properties that are suitable for drug development program. Therefore, we … analysis, hence,
required further experimental validation to translate it into a safe and effective medication …