Synaptic Architectural Alterations in CA1 and CA3 of the Ventral Hippocampus in Age-Associated Cognitively Impaired Rats

AE Rogalsky - 2023 - search.proquest.com
… We determined an estimated total number of synapses from each rat in each region, and
used a one-way ANOVA to compare the group means. In CA1, we found that there was an …

[HTML][HTML] Advanced age has dissociable effects on hippocampal CA1 ripples and CA3 high frequency events in male rats

NM DiCola, AL Lacy, OJ Bishr, KM Kimsey… - Neurobiology of …, 2022 - Elsevier
… this region have not been investigated in aged rats. The current experiment was designed to
… the extent that age-related changes in CA1 ripples were related to alterations in CA3 HFEs …

Alterations in intrinsic and synaptic properties of hippocampal CA1 VIP interneurons during aging

R Francavilla, A Guet-McCreight, S Amalyan… - Frontiers in cellular …, 2020 - frontiersin.org
… in intrinsic properties associated with age-related modifications of active properties of I-S3 …
conductances we observed that the age-related changes seen experimentally were best …

Age-related LTCC and NMDAR expression in the hippocampus and olfactory cortex in rats

A Maziar - 2022 - research.library.mun.ca
… In hippocampus and PC there was no age-related alteration of … that in hybrid Fischer 344 X
Brown Norway aged rats, there is … age-related increase in Cav1.2 surface expression in CA1

Aged rats exhibit altered behavior-induced oscillatory activity, place cell firing rates, and spatial information content in the CA1 region of the hippocampus

LM Crown, DT Gray, LA Schimanski… - Journal of …, 2022 - Soc Neuroscience
… gamma and theta frequencies in rats, although how age alters … the hippocampus CA1 region
of young and old male rats as they … Finally, aged rats had reduced within-field firing rates but …

Aging differentially affects LTCC function in hippocampal CA1 and piriform cortex pyramidal neurons

A Maziar, TN Critch, S Ghosh, V Rajani… - Cerebral …, 2023 - academic.oup.com
… , contributing to age-related cognitive dysfunction and memory … in comparison with CA1
age-dependent LTCC alterations that … early potentiation of the hippocampal DG occurs when rats

Age-dependent Effects of Dopamine on Working Memory and Synaptic Plasticity in Hippocampal CA3-CA1 Synapses in Mice

F Bakhtiarzadeh, K Shahpasand, A Shojaei… - Neuroscience, 2023 - Elsevier
… transmission, and long-term potentiation (LTP) induction and … In rats, age-related decrements
in dopamine was more than … to clarify dopamine’s age-related action. Measuring the …

Partial microglial depletion is associated with impaired hippocampal synaptic and cognitive function in young and aged rats

B Yegla, J Boles, A Kumar, TC Foster - Glia, 2021 - Wiley Online Library
… We observed age-related differences in microglial number and … –24 months old) male
Fischer-344 rats were obtained from the … For region CA1, aged control rats exhibited a significantly …

Calcium signaling during brain aging and its influence on the hippocampal synaptic plasticity

A Kumar - Calcium Signaling, 2020 - Springer
… of the complexity of age-related alterations in neuronal Ca 2… how these alterations in Ca
2+ signaling in the CA1 region of … suggest that microglia can potentiate the NMDA receptor-…

Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors

M Temido-Ferreira, DG Ferreira, VL Batalha… - Molecular …, 2020 - nature.com
… it can induce either long-term potentiation (LTP) or long-term … alterations in LTD during
normal aging and age-related … of CA1 neurons from Tg(CaMKII-hA 2A R) and WT rats. No …