[HTML][HTML] Age-related changes in species-typical behaviours in the 5xFAD mouse model of Alzheimer's disease from 4 to 16 months of age

TP O'Leary, RE Brown - Behavioural Brain Research, 2024 - Elsevier
… , whisking behaviour [34], motor function [42], [77], and social … the behaviour of female 5xFAD
and wild-type mice in a cross-… age-related changes in species typical behaviors in 5xFAD

Behaviour Hallmarks in Alzheimer's Disease 5xFAD Mouse Model

MS Pádua, JL Guil-Guerrero, PA Lopes - International Journal of …, 2024 - mdpi.com
… psychological condition and the social behaviour of individuals. … that 5xFAD mice exhibit
no changes in behaviour related to … from 5 months old with an age-related progression as the …

Behavioural and psychological symptoms of dementia in mouse models of Alzheimer's disease-related pathology

F Kosel, JMS Pelley, TB Franklin - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
… Tg mouse models of AD show social withdrawal and … -AD, 5xFAD, and APP23 models.
Current evidence suggests that … (6 months); age-related increase of pathogenic tau throughout …

Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease

S Forner, S Kawauchi, G Balderrama-Gutierrez… - Scientific data, 2021 - nature.com
… the closed arms indicating decreased anxiety behaviors (Fig. 2i–l… in social interaction 18,19
. Also, it is well established that … for lysosomes reveals age-related changes of 5xFAD mice in …

… Behaviour and Neural Activity in the 5xFAD Mouse Model of Alzheimer's Disease: Exploring Behavioural and Psychological Symptoms of Dementia in a Mouse Model …

F Kosel - 2023 - dalspace.library.dal.ca
… in this area in transgenic 5xFAD mice. Overall, these findings … neural activity and behavioural
changes resulting from AD-… an age-related reduction in social investigation in 5xFAD

Reduced social investigation and increased injurious behavior in transgenic 5xFAD mice

F Kosel, JS Hamilton, SL Harrison… - Journal of …, 2021 - Wiley Online Library
… We measured home-cage behaviors in 5xFAD males housed … social investigation in the
5xFAD transgenic mouse model of … age-related decrease in social interest by transgenic 5xFAD

Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease

…, A Locci, H Orellana, I Haupfear, S Dominguez… - Neurobiology of …, 2023 - Elsevier
… -like behaviors in 5xFAD mice, one of the most studied transgenic mouse models of AD. The
… relative to the mean and standard deviation (SD) of same-age WT controls so that changes

Age related weight loss in female 5xFAD mice from 3 to 12 months of age

WH Gendron, E Fertan, S Pelletier, KM Roddick… - Behavioural Brain …, 2021 - Elsevier
… The 5xFAD mouse model shows age-related weight loss … Our first hypothesis was that
changing the method of food … Social isolation has also been identified as a risk factor for AD in …

Intact olfactory memory in the 5xFAD mouse model of Alzheimer's disease from 3 to 15 months of age

TP O'leary, KR Stover, HM Mantolino, S Darvesh… - Behavioural Brain …, 2020 - Elsevier
… The extent to which AD mouse models show age-related5xFAD mouse is a valuable
animal model of AD because it develops many of the neurobiological and behavioural changes

Sex differences in behavior and molecular pathology in the 5XFAD model

A Sil, A Erfani, N Lamb, R Copland… - … Alzheimer's Disease, 2022 - content.iospress.com
murine models of amyloid pathology, the 5X Familial AD … 4B) during SI trials; female 5XFAD
mice visited the social partner … interaction behaviors, with an additional dependency on sex. …