… volume stress and many other problems. Initially, it is adaptively against increased workload
or defects in the efficiency of contractile … and in vivo, however, chronic Akt overexpression is …

… Besides, PI3Kα may regulate cardiac fibrosis via affecting the myocardial contractility since
… or rapamycin in vivo. However, the Akt inhibitors possess the ability to induce an increase in …

… TANK knockdown decreased the cell size and expression of … -associated enlarged cell size,
impaired contractile function, and … TANK aggravates cardiac hypertrophy in vitro and in vivo. …

… the animals 7 days after the induction of cardiac hypertrophy (… equal volume of saline was
administered to the control mice. … in vivo, we conducted AB surgery in AKT1 knockout mice (Fig…

… WT mice exhibited markedly reduced of cardiac contractile … AKT/mTOR signaling) and
upregulation of p-AKT in WT mice … autophagy in vivo, we treated WT or ATGL KO mice with …

… -induced cardiac hypertrophy and fibrosis in vivo, and determined the underlying mechanism
whether involved PTEN/AKT/… administration improved the left ventricular contractile function …

… the context of physiological cardiac hypertrophy in vivo. The key finding … Both FoxO1 and
FoxO3 can regulate heart size. … In the current study, both pAkt/Akt ratio and total IGF1R protein …

… myocardial contractility [112,113,114]. Although this type of cell death is most induced after
… Moreover, miR-145 promotes autophagy and reduces the infarct size in AMI models in vivo …

… reduced infarct size and improved cardiac function. … (I:C) induced interaction between TLR3
and PI3K in vivo, which … from cardiac contractile dysfunction, which indicated by increased …

… to characterize cardiac function and morphology in vivo. … exacerbates infarct size and recovery
of myocardial contractility after … weights associated with the activation of Akt and ribosomal …