[HTML][HTML] … -based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism

L Zhu, W Pei, I Thiele… - PLOS Computational …, 2021 - journals.plos.org
… the pharmacokinetics of ethanol metabolism through alcohol … based pharmacokinetic (PBPK)
model with a whole-body genome… the absorption, distribution, metabolism, and elimination (…

Influence of age and sex on alcohol pharmacokinetics and subjective pharmacodynamic responses following intravenous alcohol exposure in humans

V Vatsalya, ND Byrd, BL Stangl, R Momenan… - Alcohol, 2023 - Elsevier
… effects on alcohol elimination rates and subjective responses, it limits the ability to examine
sex- and age-related differences in absorption and first-pass metabolism of alcohol. These …

Effect of single‐dose, oral enzymatic porcine placental extract on pharmacokinetics of alcohol and liver function in rats

HJ Kim, S Kim, JS Seo, GW Bae… - Alcoholism: Clinical …, 2020 - Wiley Online Library
… In the alcohol pharmacokineticsabsorption of alcohol in the gastrointestinal tract. Therefore,
this may be useful in preventing hangover effects and toxicity after drinking alcohol and may …

Microphysiological systems in absorption, distribution, metabolism, and elimination sciences

KP Van Ness, F Cesar, CK Yeung… - Clinical and …, 2022 - Wiley Online Library
The use of microphysiological systems (MPS) to support absorption, distribution, metabolism,
and elimination (ADME) sciences has grown substantially in the last decade, in part driven …

Absorption, distribution, metabolism, and excretion of nanocarriers in vivo and their influences

A Zhang, K Meng, Y Liu, Y Pan, W Qu, D Chen… - Advances in colloid and …, 2020 - Elsevier
It is our goal that this review will promote an in-depth understanding of the pharmacokinetics
and fates of NCs in vivo, which will provide a solid and reliable foundation for future clinical …

Chronic alcohol consumption increased bile acid levels in enterohepatic circulation and reduced efficacy of irinotecan

X Gong, Q Zhang, Y Ruan, M Hu, Z Liu… - … and Alcoholism, 2020 - academic.oup.com
alcohol administration on pharmacokinetics of irinotecan. The … It was found in this study that
the expression of transporter … % ethanol administration, which mainly increased the excretion

[HTML][HTML] Biomarkers of moderate alcohol intake and alcoholic beverages: A systematic literature review

M Trius-Soler, G Praticò, G Gürdeniz, M Garcia-Aloy… - Genes & nutrition, 2023 - Springer
pharmacokinetics) in order to identify other potential foods containing the biomarker or its
peak level and total EtG excretion in 24 volunteers after drinking 48 g of alcohol as beer [58]…

Absorption, distribution, metabolism, and excretion of the main olive tree phenols and polyphenols: A literature review

S Galmés, B Reynés, M Palou… - Journal of Agricultural …, 2021 - ACS Publications
… 2-(3,4-dihydroxyphenyl)ethanol (DPE) metabolite, was appreciable 2 min after its administration.
excretion in 24 h urine. No linear pharmacokinetics after oral administration of different …

[图书][B] Drug disposition and pharmacokinetics: principles and applications for medicine, toxicology and biotechnology

SH Curry, R Whelpton - 2022 - books.google.com
absorption, distribution, metabolism, and excretion ofdrugs,withmathematical
assessmentsofplasmaand body … to aspirin tablets and headache and drinking of alcohol. …

A population pharmacokinetic analysis of PF-5190457, a novel ghrelin receptor inverse agonist in healthy volunteers and in heavy alcohol drinkers

E Cobbina, MR Lee, L Leggio, F Akhlaghi - Clinical pharmacokinetics, 2021 - Springer
… potential to treat alcohol use disorder. We present a population pharmacokinetic model for
… first-order absorption, first-order elimination, and proportional error was able to describe the …