High-dose baclofen attenuates insula activation during anticipatory anxiety in treatment-seeking alcohol dependant individuals: Preliminary findings from a pharmaco …
… baclofen administration attenuates activation in the insula and … emotional regulation and
attentional allocation during high … observed in the left anterior insula and inferior operculum. …
attentional allocation during high … observed in the left anterior insula and inferior operculum. …
Low versus high level of response to alcohol affects amygdala functional connectivity during processing of emotional stimuli
BS McKenna, RM Anthenelli, TL Smith… - Alcoholism: Clinical …, 2022 - Wiley Online Library
… suggest impaired affective processing in nonheavy drinking … patterns found were attenuation
of amygdala connectivity with … Regional brain differences, especially in the anterior insula …
of amygdala connectivity with … Regional brain differences, especially in the anterior insula …
[HTML][HTML] Anterior insula stimulation suppresses appetitive behavior while inducing forebrain activation in alcohol-preferring rats
M Haaranen, G Scuppa, S Tambalo, V Järvi… - Translational …, 2020 - nature.com
… with attention, executive function, and emotions, making it a potential target region for …
Anterior insula stimulation by the excitatory Gq-DREADDs significantly attenuated both alcohol …
Anterior insula stimulation by the excitatory Gq-DREADDs significantly attenuated both alcohol …
The role of anterior insula–brainstem projections and alpha-1 noradrenergic receptors for compulsion-like and alcohol-only drinking
T De Oliveira Sergio, K Lei, C Kwok, S Ghotra… - …, 2021 - nature.com
… emotional state, and compulsive alcohol … activation in forebrain cortical areas [19], we set
out to examine how the NE system, including interactions with insula, might regulate alcohol …
out to examine how the NE system, including interactions with insula, might regulate alcohol …
Positive alcohol expectancy and resting-state functional connectivity of the insula in problem drinking
… regions involved in negative emotion processing and self-control, … Previous studies have
demonstrated attenuated vmPFC … within the right dorsal anterior insula network was associated …
demonstrated attenuated vmPFC … within the right dorsal anterior insula network was associated …
Neural responses to the implicit processing of emotional facial expressions in binge drinking
… To evaluate implicit emotion processing, we used an experimental … processing, decreased
activations is found in the insula, … , amygdala activation supports the existence of emotional …
activations is found in the insula, … , amygdala activation supports the existence of emotional …
Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol
… estimates of alcohol effects at high levels of activation (1 SD … anterior insula, reported greater
stimulation following alcohol … , the insula is responsive to motivationally and emotionally …
stimulation following alcohol … , the insula is responsive to motivationally and emotionally …
[HTML][HTML] Chemogenetic stimulation and silencing of the insula, amygdala, nucleus accumbens, and their connections differentially modulate alcohol drinking in rats
M Haaranen, A Schäfer, V Järvi… - Frontiers in behavioral …, 2020 - frontiersin.org
… In the anterior insula and amygdala, excitatory Gq-DREADDs significantly attenuated alcohol
… Activation of the anterior insula connections with the nucleus accumbens and amygdala is …
… Activation of the anterior insula connections with the nucleus accumbens and amygdala is …
… alcohol use disorder severity among nontreatment‐seeking heavy drinkers: An examination of the incentive salience and negative emotionality domains of the alcohol …
… in heavy drinking samples have examined brain activation … are suggestive of an attenuation
of emotional responses to stress-… Furthermore, the emotional-attenuating effects of alcohol …
of emotional responses to stress-… Furthermore, the emotional-attenuating effects of alcohol …
Bilateral insular cortical lesions reduce sensitivity to the adverse consequences of acute ethanol intoxication in Pavlovian conditioning procedures
A Mukherjee, EA Gilles‐Thomas… - Alcohol: Clinical and …, 2024 - Wiley Online Library
… acid lesions of the insular cortex (Figure 6) significantly attenuated EtOH-induced CTA and
… We have previously demonstrated a correlation between reduced IC activation and a loss of …
… We have previously demonstrated a correlation between reduced IC activation and a loss of …