ASIC1a promotes synovial invasion of rheumatoid arthritis via Ca2+/Rac1 pathway

R Niu, X Hang, Y Feng, Y Zhang, X Qian, S Song… - International …, 2020 - Elsevier
regulator of synovial invasion via Ca 2+ /Rac1 pathway. … of tumor-like cells, they escape
the growth limits of contact … of amiloride sensitive voltage-independent cationic channels, …

[HTML][HTML] Expression profiles of ASIC1/2 and TRPV1/4 in common skin tumors

K Ackermann, S Wallner, C Brochhausen… - International Journal of …, 2021 - mdpi.com
… role in the regulation of cell apoptosis and survival by regulating calcium … inhibitors lead to
a significant reduction in tumor growth in … Inhibiting this current reduces glioma growth and cell

[HTML][HTML] Pulmonary endothelial cells from different vascular segments exhibit unique recovery from acidification and Na+/H+ exchanger isoform expression

D Adams, CS Choi, SL Sayner - Plos one, 2022 - journals.plos.org
… This study contributes to the growing understanding that … expression of the less
amiloride-sensitive NHE isoforms, NHE3 or -4… growth, cell proliferation and invasion through …

[HTML][HTML] Targeting SGK1 enhances the efficacy of radiotherapy in locally advanced rectal cancer

C Zhou, W Xiao, T Jiang, Z Guo, M Li, H Chang… - Biomedicine & …, 2020 - Elsevier
… SGK1 regulates the amiloride-sensitive sodium channel, … of ATF3 increased the radioresistance
in these cell lines by … that SGK1 expression is up-regulated in non-pCR LARC. The …

[HTML][HTML] A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma

S Langthaler, T Rienmüller, S Scheruebel… - PLoS Computational …, 2021 - journals.plos.org
… activation in S-G2/M phase initiation, although this does not lead to a noticeable increase of
… ), amiloride sensitive sodium channels (ENaCs) and the CFTR chloride channels, regulated

System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases

MS Hossen, A Samad, F Ahammad… - Bioscience …, 2022 - portlandpress.com
… , and numerous critical regulatory and associated drug … either stimulate or prevent tumor
growth. In advanced renal … epithelial 1 β subunit The amiloride-sensitive SCNN1B gene …

[HTML][HTML] COMMD proteins function and their regulating roles in tumors

G You, C Zhou, L Wang, Z Liu, H Fang, X Yao… - Frontiers in …, 2023 - frontiersin.org
… ENaC is an amiloride-sensitive Na + channel, and is … in Hela cells increased the amount of
CFTR on the cell surface, … -apoptosis, NF-κB may contribute to oncogenesis. It is believed that …

Na/H Exchangers in Epithelia

PR Kiela, H Xu, FK Ghishan - … of Epithelial Transporters and Ion Channels, 2020 - Springer
… of ion channels and transporters has been proposed to contribute to cell migration in large
part through local volume regulation. … the cell cycle is accompanied by increased cell volume. …

[HTML][HTML] Fibrinolytic system and cancer: diagnostic and therapeutic applications

N Mahmood, SA Rabbani - International journal of molecular sciences, 2021 - mdpi.com
… of various growth factors and cytokines, regulation of immune … ], and blocking plasmin activity
may lead to systemic disorders. … In SNB19 glioma cells, RNAi-mediated repression of uPA …

Specificity in Glia-Neuron Interactions

S Ray - 2023 - search.proquest.com
… function, glial ionic regulation of sensory cell/NRE milieu can … bud cells to express
amiloride-sensitive ENaC Na+ channels. … amiloride-sensitive currents and migration in human