… This chapter will focus on the pharmacokinetic determinants … of agents (eg, antibiotics and
anticonvulsants) in neonates and … In preterm premature rupture of the membranes at less than …

… Intrapartum antibiotics may prevent vertical transmission of GBS from colonized mothers to
… the opportunity provided by the temporary unavailability of first-choice antibiotics in Brazil. …

… of spontaneous preterm-birth among pregnant women living with HIV on antiretroviral therapy
(ART) is 3- to 4-fold higher when compared to HIV-negative women… intrapartum antibiotics …

… Despite improvements in medical technology and the use of prenatal medications, such as
antibiotics and corticosteroids, infants born at 22–24 weeks GA suffer from a high prevalence …

… Citation59 The analysis of the pharmacokinetic nature of penicillin including amoxicillin
shows that it is primarily eliminated unchanged in the urine, Citation60 yet simple urinalysis and …

… of pharmacokinetic data of the specific population and specific disease may increase the risk
of unreasonable use of antibiotics… a pharmacokinetic analysis of cefotaxime in EOS patients …

… prescribed antibiotics during pregnancy in the USA and in European countries [1,2,3,4]. In
particular, azithromycin, a second-generation macrolide, has a better pharmacokinetic profile …

… Let's apply these factors to a typical clinical situation: weight-based dosing of aminoglycoside
antibiotics. These antibiotics are hydrophilic and diffuse freely in water (high V; tobramycin…

… a result of a premature rupture of ovular membranes (20–30%… If endocervical culture is
positive, the antibiotics will be … , the pharmacokinetic parameters observed in the pregnant …

… as premature rupture of membranes (PROM) and signs of sepsis before birth, broad spectrum
antibiotics are usually administered to the mother… However, several small pharmacokinetic …