Apoptosis in the fetal testis eliminates developmentally defective germ cell clones
… our hypothesis that earlier errors in germ-cell epigenetic … that apoptosis during male germline
development functions as a … , diffusible apoptotic signals are therefore not necessary for …
development functions as a … , diffusible apoptotic signals are therefore not necessary for …
Actions and roles of FSH in germinative cells
… in the induction of germ cells and germ-cell-like cells in vitro. … germ cells, it regulates and
limits the wave of apoptosis of … for functional germ cells. They are fundamental to protecting …
limits the wave of apoptosis of … for functional germ cells. They are fundamental to protecting …
During infancy low levels of follicle-stimulating hormone may result in high rate of germ cell apoptosis
… act as a factor essential for promoting germ cell survival in the … wave of spermatogenesis,
which is after minipuberty and at … the role of FSH in germ cell apoptosis during early infancy in …
which is after minipuberty and at … the role of FSH in germ cell apoptosis during early infancy in …
A matter of new life and cell death: programmed cell death in the mammalian ovary
MS Chesnokov, AR Mamedova, B Zhivotovsky… - Journal of Biomedical …, 2024 - Springer
… —progenitor germ cell … an essential element in ovarian development, functions and
pathologies. A thorough understanding of molecular mechanisms regulating PCD events is required …
pathologies. A thorough understanding of molecular mechanisms regulating PCD events is required …
Global changes in epigenomes during mouse spermatogenesis: possible relation to germ cell apoptosis
T Koji, Y Shibata - Histochemistry and Cell Biology, 2020 - Springer
… of such trigger may require a thorough understanding of the … cell death in the first and third
peaks is regarded as apoptosis… On the other hand, DNMT3a and DNMT3b function primarily …
peaks is regarded as apoptosis… On the other hand, DNMT3a and DNMT3b function primarily …
The beginning of meiosis in mammalian female germ cells: a never-ending story of intrinsic and extrinsic factors
D Farini, M De Felici - International Journal of Molecular Sciences, 2022 - mdpi.com
… during migration via the suppression of apoptosis [86], either … in male germ cells; however,
no specific functions of the … mitotic germ cells and sharply increased in early meiotic cells…
no specific functions of the … mitotic germ cells and sharply increased in early meiotic cells…
[HTML][HTML] Sertoli cells as key drivers of testis function
L O'Donnell, LB Smith, D Rebourcet - Seminars in Cell & Developmental …, 2022 - Elsevier
… levels of germ cell apoptosis that can vary between cell types … In summary, Sertoli cells are
essential for the establishment … are first produced at puberty, well after the establishment of the …
essential for the establishment … are first produced at puberty, well after the establishment of the …
Research progress on the role and mechanism of DNA damage repair in germ cell development
Y Wang, M Su, Y Chen, X Huang, L Ruan… - Frontiers in …, 2023 - frontiersin.org
… can damage the function and morphology of germ cells and even … that defective ovum death
and germ cell apoptosis may be … First, we introduce the mechanisms, repair methods, and …
and germ cell apoptosis may be … First, we introduce the mechanisms, repair methods, and …
Studying human reproductive biology through single-cell analysis and in vitro differentiation of stem cells into germ cell-like cells
L Li, R Yang, C Yin, K Kee - Human Reproduction Update, 2020 - academic.oup.com
… To validate the functional roles of these gene markers, … some genetic requirements are unique
in human germ cells and … aged early-stage monkey oocytes, and increased apoptosis plus …
in human germ cells and … aged early-stage monkey oocytes, and increased apoptosis plus …
[HTML][HTML] Updates in Sertoli cell-mediated signaling during spermatogenesis and advances in restoring Sertoli cell function
VA Ruthig, DJ Lamb - Frontiers in endocrinology, 2022 - frontiersin.org
… The time necessary for a germ cell to go from type A … germ cell development from
meiotic initiation to early prophase. Germ cells in these mice that did not undergo apoptosis …
meiotic initiation to early prophase. Germ cells in these mice that did not undergo apoptosis …